As a neuromodulator, the neurotransmitter acetylcholine plays an important role in cognitive,
mood, locomotor, sleep/wake, and olfactory functions. In the pathophysiology of most …

This article presents an overview of imaging agents for PET that have been applied for
research and diagnostic purposes in patients affected by dementia. Classified by the target …

The study of nicotinic acetylcholine receptors (nAChRs) has significantly progressed in the
last decade, due to a) the improved techniques available for structural studies; b) the …

Since the inline positron emission tomography (PET)/magnetic resonance imaging (MRI)
system appeared in clinical, more than a decade has passed. In this article, we have …

With appropriate radiotracers, positron emission tomography (PET) allows direct or indirect
monitoring of the spatial and temporal distribution of anesthetics, neurotransmitters, and …

Even though language is essential in human communication, research on pharmacological
therapies for language deficits in highly prevalent neurodegenerative and vascular brain …

Background: Alzheimer's disease (AD) is a progressive neurodegenerative disease of
growing interest given that there is cognitive damage and symptom onset acceleration …

Background Inflammatory mechanisms are believed to contribute to the manifestation of
major depressive disorder (MDD). Central cholinergic activity may moderate this effect …

(1) Background: Tauopathies are a group of diseases characterized by the deposition of
abnormal tau protein. They are distinguished into 3R, 4R, and 3R/4R tauopathies and also …

There is evidence of early pathological changes in cholinergic neurons of patients with
Alzheimer's disease and Lewy body disease. This makes cholinergic molecular imaging one …