Cutaneous lupus erythematosus: an update on pathogenesis and future therapeutic directions
D Niebel, L de Vos, T Fetter, C Brägelmann… - American Journal of …, 2023 - Springer
Lupus erythematosus comprises a spectrum of autoimmune diseases that may affect various
organs (systemic lupus erythematosus [SLE]) or the skin only (cutaneous lupus …
organs (systemic lupus erythematosus [SLE]) or the skin only (cutaneous lupus …
Systemic lupus erythematosus: one year in review 2023
D Zucchi, E Silvagni, E Elefante, V Signorini… - Clinical and …, 2023 - sfera.unife.it
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of
clinical manifestations and a relapsing-remitting course. New data regarding pathogenic …
clinical manifestations and a relapsing-remitting course. New data regarding pathogenic …
Relationship of systemic type I interferon activity with clinical phenotypes, disease activity, and damage accrual in systemic lupus erythematosus in treatment-naive …
K Miyachi, T Iwamoto, S Kojima, T Ida, J Suzuki… - Arthritis Research & …, 2023 - Springer
Background Systemic lupus erythematosus (SLE) is heterogeneous in organ involvement
and disease severity, presenting a broad clinical phenotype. Systemic type I interferon (IFN) …
and disease severity, presenting a broad clinical phenotype. Systemic type I interferon (IFN) …
Plasmacytoid Dendritic Cells Are Not Major Producers of Type 1 IFN in Cutaneous Lupus: An In-Depth Immunoprofile of Subacute and Discoid Lupus
The immunologic drivers of cutaneous lupus erythematosus (CLE) and its clinical subtypes
remain poorly understood. We sought to characterize the immune landscape of discoid …
remain poorly understood. We sought to characterize the immune landscape of discoid …
Litifilimab (BIIB059), a promising investigational drug for cutaneous lupus erythematosus
SK Cho, T Vazquez, VP Werth - Expert Opinion on Investigational …, 2023 - Taylor & Francis
Introduction There are no US Food and Drug Administration (FDA) approved therapies for
cutaneous lupus erythematosus (CLE). Litifilimab is a monoclonal antibody against BDCA2 …
cutaneous lupus erythematosus (CLE). Litifilimab is a monoclonal antibody against BDCA2 …
Emerging immunotherapeutic strategies for cutaneous lupus erythematosus: an overview of recent phase 2 and 3 clinical trials
D Lim, J Kleitsch, VP Werth - Expert Opinion on Emerging Drugs, 2023 - Taylor & Francis
Introduction Cutaneous lupus erythematosus (CLE) is an autoimmune disease that is
clinically heterogenous and may occur with or without the presence of systemic lupus …
clinically heterogenous and may occur with or without the presence of systemic lupus …
Granzyme serine proteases in inflammation and rheumatic diseases
Granzymes (granule-secreted enzymes) are a family of serine proteases that have been
viewed as redundant cytotoxic enzymes since their discovery more than 30 years ago …
viewed as redundant cytotoxic enzymes since their discovery more than 30 years ago …
Modulation of immune cells as a therapy for cutaneous lupus erythematosus
Cutaneous lupus erythematosus (CLE) is an autoimmune disorder like systemic lupus
erythematosus (SLE). Both SLE and CLE characterize autoantibody secretion and immune …
erythematosus (SLE). Both SLE and CLE characterize autoantibody secretion and immune …
Recent advances in cutaneous lupus
MP Maz, JWS Martens, A Hannoudi, AL Reddy… - Journal of …, 2022 - Elsevier
Cutaneous lupus erythematosus (CLE) is an inflammatory and autoimmune skin condition
that affects patients with systemic lupus erythematosus (SLE) and exists as an isolated entity …
that affects patients with systemic lupus erythematosus (SLE) and exists as an isolated entity …
Comprehensive analysis of cell lineages involved in giant cell arteritis pathogenesis using highly multiplexed imaging mass cytometry
M Robert, LA Chépeaux, Y Glasson… - Autoimmunity …, 2023 - pubmed.ncbi.nlm.nih.gov
Comprehensive analysis of cell lineages involved in giant cell arteritis pathogenesis using
highly multiplexed imaging mass cytometry Comprehensive analysis of cell lineages involved in …
highly multiplexed imaging mass cytometry Comprehensive analysis of cell lineages involved in …