Multiple sclerosis (MS) has long been regarded as a chronic inflammatory disease of the
white matter that leads to demyelination and eventually to neurodegeneration. In the past …

There is increasing evidence for the involvement of mitochondrial dysfunction and oxidative
stress in the pathogenesis of many of the major neurodegenerative and neuroinflammatory …

Available therapies for multiple sclerosis patients, while effective during the relapsing phase,
have little benefit for progressive multiple sclerosis patients. Development of therapies to …

The greatest unmet need in multiple sclerosis (MS) are treatments that delay, prevent or
reverse progression. One of the most tractable strategies to achieve this is to therapeutically …

Objective To evaluate the association between the damage to the anterior and posterior
visual pathway as evidence of the presence of retrograde and anterograde trans‐synaptic …

Background Multiple sclerosis (MS) is a stressful condition; depression, anxiety, pain and
fatigue are all common problems. Mindfulness based interventions (MBIs) mitigate stress …

Remyelination failure in multiple sclerosis (MS) contributes to progression of disability. The
deficient repair results from neuroinflammation and deposition of inhibitors including …

Using a philosophical approach or deductive reasoning, we challenge the dominant clinico-
radiological worldview that defines multiple sclerosis (MS) as a focal inflammatory disease …

T helper (Th) 17 cells are considered to contribute to inflammatory mechanisms in diseases
such as multiple sclerosis (MS). However, the discussion persists regarding their true role in …

After spinal cord injury (SCI) there is prolonged and dispersed oligodendrocyte cell death
that is responsible for widespread demyelination. To regenerate this lost myelin, many …