ets‐1 is transcriptionally up‐regulated by H2O2 via an antioxidant response element

LA Wilson, A Gemin, R Espiritu, G Singh - The FASEB Journal, 2005 - Wiley Online Library
Expression of the transcription factor Ets‐1 is increasingly associated with the progression of
several human cancers. A tumor‐derived factor is expected to be involved in the …

Mechanisms associated with mitochondrial-generated reactive oxygen species in cancer

ML Verschoor, LA Wilson… - Canadian journal of …, 2010 - cdnsciencepub.com
The mitochondria are unique cellular organelles that contain their own genome and, in
conjunction with the nucleus, are able to transcribe and translate genes encoding …

Cyclooxygenase isoenzyme-2 and vascular endothelial growth factor are associated with poor prognosis in esophageal adenocarcinoma

MJD Prins, RJJ Verhage, FJW ten Kate… - Journal of …, 2012 - Elsevier
Abstract Background Cyclooxygenase isoenzyme-2 (COX-2) and vascular endothelial
growth factor (VEGF) contribute to angiogenesis and are overexpressed in various …

The transcription factor ETS-1: its role in tumour development and strategies for its inhibition

JC Hahne, AF Okuducu, A Sahin… - Mini reviews in …, 2008 - ingentaconnect.com
Transcription factors are an important group of proteins. Changes in expression or activity of
transcription factors result in diverse and manifold effects on the whole transcriptome of the …

[PDF][PDF] VEGF as a predictor for response to definitive chemoradiotherapy and COX-2 as a prognosticator for survival in esophageal squamous cell carcinoma

MS Yoon, TK Nam, JS Lee, SH Cho… - Journal of Korean …, 2011 - synapse.koreamed.org
We investigated the patterns of pretreatment expression of the epidermal growth factor
receptor (EGFR), vascular endothelial growth factor (VEGF), and cyclooxygenase-2 (COX-2) …

The role of ets factors in tumor angiogenesis

P Oettgen - Journal of oncology, 2010 - Wiley Online Library
Angiogenesis is a critical component of tumor growth. A number of growth factors, including
VEGF, FGF, and HGF, have been implicated as angiogenic growth factors that promote …

Transcriptional silencing of ETS-1 abrogates epithelial-mesenchymal transition resulting in reduced motility of pancreatic cancer cells

C Li, Z Wang, YAN Chen, M Zhou… - Oncology …, 2015 - spandidos-publications.com
Abstract v-ets erythroblastosis virus E26 oncogene homolog 1 (ETS-1) plays crucial roles in
a spectrum of malignancies. ETS-1 has gained attention in cancer research for its …

Lymphangiogenesis in Esophageal Adenocarcinomas--Lymphatic Vessel Density as Prognostic Marker in Esophageal Adenocarcinoma

RS Saad, JL Lindner, Y Liu… - American journal of …, 2009 - academic.oup.com
We studied tumor lymphatic vascular density (LVD) as a predictive marker for the risk of
lymph node (LN) metastasis and its relationship to other prognostic parameters and survival …

Identification and validation of esophageal squamous cell carcinoma targets for fluorescence molecular endoscopy

X Zhao, Q Huang, M Koller, MD Linssen… - International Journal of …, 2021 - mdpi.com
Dysplasia and intramucosal esophageal squamous cell carcinoma (ESCC) frequently go
unnoticed with white-light endoscopy and, therefore, progress to invasive tumors. If suitable …

[引用][C] 血管内皮生长因子在消化系肿瘤中的研究进展

徐伟, 刘政, 季国忠 - 医学研究生学报, 2009