Allergic rhinitis and its impact on asthma

J Bousquet, P Van Cauwenberge… - Journal of allergy and …, 2001 - jacionline.org
Allergic rhinitis is clinically defined as a symptomatic disorder of the nose induced by an IgE-
mediated inflammation after allergen exposure of the membranes lining the nose. Symptoms …

The recombinant allergen‐based concept of component‐resolved diagnostics and immunotherapy (CRD and CRIT)

VALENTA, LIDHOLM… - Clinical & …, 1999 - search.ebscohost.com
Current forms of allergy diagnosis and specific immunotherapy are performed with allergen
extracts. Allergen extracts contain a variety of allergenic and nonallergenic components and …

Structural and functional aspects of PR‐10 proteins

H Fernandes, K Michalska, M Sikorski… - The FEBS …, 2013 - Wiley Online Library
Physical, chemical and biological stress factors, such as microbial infection, upregulate the
transcription levels of a number of plant genes, coding for the so‐called pathogenesis …

Current overview of allergens of plant pathogenesis related protein families

M Sinha, RP Singh, GS Kushwaha… - The Scientific World …, 2014 - Wiley Online Library
Pathogenesis related (PR) proteins are one of the major sources of plant derived allergens.
These proteins are induced by the plants as a defense response system in stress conditions …

Tree pollen allergens—an update from a molecular perspective

C Asam, H Hofer, M Wolf, L Aglas, M Wallner - Allergy, 2015 - Wiley Online Library
It is estimated that pollen allergies affect approximately 40% of allergic individuals. In
general, tree pollen allergies are mainly elicited by allergenic trees belonging to the orders …

The family 10 of plant pathogenesis-related proteins: their structure, regulation, and function in response to biotic and abiotic stresses

JJ Liu, AKM Ekramoddoullah - Physiological and molecular plant …, 2006 - Elsevier
The aim of this review is to present the current state of our understanding on the structure,
regulation, and function of plant pathogenesis-related protein family 10 (PR-10). This protein …

[HTML][HTML] Allergen extracts for in vivo diagnosis and treatment of allergy: is there a future?

R Valenta, A Karaulov, V Niederberger… - The Journal of Allergy …, 2018 - Elsevier
Today, in vivo allergy diagnosis and allergen-specific immunotherapy (AIT) are still based
on allergen extracts obtained from natural allergen sources. Several studies analyzing the …

AllergenOnline: a peer‐reviewed, curated allergen database to assess novel food proteins for potential cross‐reactivity

RE Goodman, M Ebisawa, F Ferreira… - Molecular nutrition & …, 2016 - Wiley Online Library
Scope Increasingly regulators are demanding evaluation of potential allergenicity of foods
prior to marketing. Primary risks are the transfer of allergens or potentially cross‐reactive …

Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1 and its likely biological function as a plant steroid carrier

Z Marković-Housley, M Degano, D Lamba… - Journal of molecular …, 2003 - Elsevier
Bet v 1l is a naturally occurring hypoallergenic isoform of the major birch pollen allergen Bet
v 1. The Bet v 1 protein belongs to the ubiquitous family of pathogenesis-related plant …

Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1: potential use of hypoallergenic isoforms for …

F Ferreira, K Hirtenlehner, A Jilek… - The Journal of …, 1996 - rupress.org
We dissected the T cell activation potency and the immunoglobulin (Ig) E-binding properties
(allergenicity) of nine isoforms of Bet v 1 (Bet v 1a-Bet v 1l), the major birch pollen allergen …