Periodontitis is a multi‐etiologic infection characterized clinically by pathologic loss of the
periodontal ligament and alveolar bone. Herpesviruses and specific bacterial species are …

As the lowest organisms possessing T cells, fish are instrumental for understanding T cell
evolution and immune defense in early vertebrates. This study established in Nile tilapia …

To better understand the role of sphingolipids in the multifactorial process of inflammatory
bowel disease (IBD), we elucidated the role of CerS4 in colitis and colitis-associated cancer …

Abstract γδ T cells are increasingly emerging as crucial immune regulators that can take on
innate and adaptive roles in the defence against pathogens. Although they arise within the …

Neddylation plays a vital role in post-translational modification, intricately shaping the
regulation of diverse biological processes, including those related to cellular immune …

Idiosyncratic drug reactions (IDRs) range from relatively common, mild reactions to rarer,
potentially life-threatening adverse effects that pose significant risks to both human health …

In addition to their central functions in translation, ribosomes can adopt inactive structures
that are fully assembled yet devoid of mRNA. We describe how the abundance of idle …

S-acylation, the reversible lipidation of free cysteine residues with long-chain fatty acids, is a
highly dynamic post-translational protein modification that has recently emerged as an …

Immune checkpoints secure the proper function of the immune system and the maintenance
of the BTLA-HVEM complex, an inhibitory immune checkpoint, is one of the pathways vital …

Simple Summary T cells are immune cells that can be used to target infections or cancers.
Adoptive T-cell immunotherapy leverages these properties and/or confers new features to T …