Tobacco and nicotine use

B Le Foll, ME Piper, CD Fowler, S Tonstad… - Nature Reviews …, 2022 - nature.com
Tobacco smoking is a major determinant of preventable morbidity and mortality worldwide.
More than a billion people smoke, and without major increases in cessation, at least half will …

Cannabidiol: pharmacology and therapeutic targets

SC Britch, S Babalonis, SL Walsh - Psychopharmacology, 2021 - Springer
Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …

Cannabidiol: a potential new alternative for the treatment of anxiety, depression, and psychotic disorders

MS García-Gutiérrez, F Navarrete, A Gasparyan… - Biomolecules, 2020 - mdpi.com
The potential therapeutic use of some Cannabis sativa plant compounds has been attracting
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …

A comprehensive review on the techniques for extraction of bioactive compounds from medicinal cannabis

HMS Al Ubeed, DJ Bhuyan, MA Alsherbiny, A Basu… - Molecules, 2022 - mdpi.com
Cannabis is well-known for its numerous therapeutic activities, as demonstrated in pre-
clinical and clinical studies primarily due to its bioactive compounds. The Cannabis industry …

The safety and efficacy of low oral doses of cannabidiol: An evaluation of the evidence

JC Arnold, D McCartney, A Suraev… - Clinical and …, 2023 - Wiley Online Library
Global interest in the non‐intoxicating cannabis constituent, cannabidiol (CBD), is
increasing with claims of therapeutic effects across a diversity of health conditions. At …

Critical aspects affecting cannabidiol oral bioavailability and metabolic elimination, and related clinical implications

E Perucca, M Bialer - CNS drugs, 2020 - Springer
This article provides a critical appraisal of the available evidence concerning clinical
exposure to orally administered cannabidiol (CBD), with special reference to factors …

The therapeutic potential of purified cannabidiol

SE O'Sullivan, SS Jensen, GN Nikolajsen… - Journal of Cannabis …, 2023 - Springer
The use of cannabidiol (CBD) for therapeutic purposes is receiving considerable attention,
with speculation that CBD can be useful in a wide range of conditions. Only one product, a …

Cannabidiol for the treatment of brain disorders: therapeutic potential and routes of administration

GTY Yau, W Tai, JC Arnold, HK Chan… - Pharmaceutical …, 2023 - Springer
The use of cannabidiol (CBD) for treating brain disorders has gained increasing interest.
While the mechanism of action of CBD in these conditions is still under investigation, CBD …

The impact of cannabis legalization for recreational purposes on youth: a narrative review of the Canadian experience

DS Rubin-Kahana, JF Crépault, J Matheson… - Frontiers in …, 2022 - frontiersin.org
Cannabis legalization for non-medical purposes (subsequently referred to as “cannabis
legalization” or “legalization”) took place in Canada in October 2018. One of the federal …

Cannabidiol protects against Alzheimer's disease in C. elegans via ROS scavenging activity of its phenolic hydroxyl groups

Y Zhang, H Li, S Jin, Y Lu, Y Peng, L Zhao… - European journal of …, 2022 - Elsevier
Recent discoveries have implicated the potential of Cannabidiol (CBD) in the prevention of
Alzheimer's disease (AD). However, how CBD affects such neurodegenerative disorders …