Autism spectrum disorder (ASD) is a complex and genetically heterogeneous
neuropsychiatric disease affecting as many as 1 in 68 children. Large scale genetic …

Astrocytes are highly involved in a multitude of developmental processes that are known to
be dysregulated in Fragile X Syndrome. Here, we examine these processes individually and …

Resting-state fMRI (rsfMRI) is a widespread method utilized for estimating brain-wide
functional connectivity (FC) in health and disease. However, the cellular underpinnings of …

Fragile X syndrome (FXS) is a neurodevelopmental disorder that is caused by mutations in
the FMR1 gene. Neuroanatomical alterations have been reported in both male and female …

Neuroimaging studies of psychiatric illness have revealed a broad spectrum of structural
and functional perturbations that have been attributed in part to the complex genetic …

Autism spectrum disorders (ASD) are considered neural dysconnectivity syndromes. To
better understand ASD and uncover potential treatments, it is imperative to know and dissect …

Psychiatric disease is one of the leading causes of disability worldwide. Despite the global
burden and need for accurate diagnosis and treatment of mental illness, psychiatric …

Age-related osteoporosis poses a significant challenge in musculoskeletal health; a
condition characterized by reduced bone density and increased fracture susceptibility in …

The biological basis of the increased risk for psychiatric disorders due to the pathogenic
15q11. 2 copy number deletion is unknown. Previous work has shown disturbances in white …

Fragile X syndrome (FXS), the most common cause of autism and inherited intellectual
disability, is caused by the mutation of a single gene, fmr1, which encodes the Fragile X …