Identification of bioactive metabolites using activity metabolomics
The metabolome, the collection of small-molecule chemical entities involved in metabolism,
has traditionally been studied with the aim of identifying biomarkers in the diagnosis and …
has traditionally been studied with the aim of identifying biomarkers in the diagnosis and …
Reconstructing organisms in silico: genome-scale models and their emerging applications
X Fang, CJ Lloyd, BO Palsson - Nature Reviews Microbiology, 2020 - nature.com
Escherichia coli is considered to be the best-known microorganism given the large number
of published studies detailing its genes, its genome and the biochemical functions of its …
of published studies detailing its genes, its genome and the biochemical functions of its …
The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk
To address how the microbiome might modify the interaction between diet and
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …
Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v. 14.0)
H Mi, A Muruganujan, X Huang, D Ebert, C Mills… - Nature protocols, 2019 - nature.com
The PANTHER classification system (http://www. pantherdb. org) is a comprehensive system
that combines genomes, gene function classifications, pathways and statistical analysis …
that combines genomes, gene function classifications, pathways and statistical analysis …
Pathway enrichment analysis and visualization of omics data using g: Profiler, GSEA, Cytoscape and EnrichmentMap
Pathway enrichment analysis helps researchers gain mechanistic insight into gene lists
generated from genome-scale (omics) experiments. This method identifies biological …
generated from genome-scale (omics) experiments. This method identifies biological …
Species-level functional profiling of metagenomes and metatranscriptomes
Functional profiles of microbial communities are typically generated using comprehensive
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …
The human gut microbiome in early-onset type 1 diabetes from the TEDDY study
Abstract Type 1 diabetes (T1D) is an autoimmune disease that targets pancreatic islet beta
cells and incorporates genetic and environmental factors, including complex genetic …
cells and incorporates genetic and environmental factors, including complex genetic …
Systems biology and multi-omics integration: viewpoints from the metabolomics research community
The use of multiple omics techniques (ie, genomics, transcriptomics, proteomics, and
metabolomics) is becoming increasingly popular in all facets of life science. Omics …
metabolomics) is becoming increasingly popular in all facets of life science. Omics …
Strains, functions and dynamics in the expanded Human Microbiome Project
The characterization of baseline microbial and functional diversity in the human microbiome
has enabled studies of microbiome-related disease, diversity, biogeography, and molecular …
has enabled studies of microbiome-related disease, diversity, biogeography, and molecular …
Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism
The human gut microbiome is linked to many states of human health and disease. The
metabolic repertoire of the gut microbiome is vast, but the health implications of these …
metabolic repertoire of the gut microbiome is vast, but the health implications of these …