Heart failure in the last year: progress and perspective

D Tomasoni, M Adamo, MS Anker… - ESC heart …, 2020 - Wiley Online Library
Research about heart failure (HF) has made major progress in the last years. We give here
an update on the most recent findings. Landmark trials have established new treatments for …

Towards precision medicine in heart failure

CS Weldy, EA Ashley - Nature Reviews Cardiology, 2021 - nature.com
The number of therapies for heart failure (HF) with reduced ejection fraction has nearly
doubled in the past decade. In addition, new therapies for HF caused by hypertrophic and …

A year in heart failure: an update of recent findings

L Stretti, D Zippo, AJS Coats, MS Anker… - ESC Heart …, 2021 - Wiley Online Library
Major changes have occurred in these last years in heart failure (HF) management.
Landmark trials and the 2021 European Society of Cardiology guidelines for the diagnosis …

Diabetes mellitus and heart failure: epidemiology, pathophysiologic mechanisms, and the role of SGLT2 inhibitors

P Theofilis, E Oikonomou, K Tsioufis, D Tousoulis - Life, 2023 - mdpi.com
Diabetes mellitus (DM) and heart failure (HF) are frequently encountered afflictions that are
linked by a common pathophysiologic background. According to landmark studies, those …

Dynamic personalized risk prediction in chronic heart failure patients: a longitudinal, clinical investigation of 92 biomarkers (Bio-SHiFT study)

D Klimczak-Tomaniak, M de Bakker, E Bouwens… - Scientific reports, 2022 - nature.com
The aim of our observational study was to derive a small set out of 92 repeatedly measured
biomarkers with optimal predictive capacity for adverse clinical events in heart failure, which …

[HTML][HTML] Big data-driven precision medicine: Starting the custom-made era of iatrology

C Song, Y Kong, L Huang, H Luo, X Zhu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Precision medicine is a new therapeutic concept and method emerging in recent years. The
rapid development of precision medicine is driven by the development of omics related …

Integrative proteomic analysis reveals the cytoskeleton regulation and mitophagy difference between ischemic cardiomyopathy and dilated cardiomyopathy

M Liu, L Zhai, Z Yang, S Li, T Liu, A Chen… - Molecular & Cellular …, 2023 - ASBMB
Ischemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM) are the two primary
etiologies of end-stage heart failure. However, there remains a dearth of comprehensive …

Finding a needle in a haystack: proteomics in heart failure

SA Michelhaugh, JL Januzzi Jr - Basic to Translational Science, 2020 - jacc.org
Circulating protein biomarkers provide information regarding pathways in heart failure (HF)
and can add important value to clinicians. Advancements in proteomics allow researchers to …

Big data approaches in heart failure research

JD Lanzer, F Leuschner, R Kramann… - Current Heart Failure …, 2020 - Springer
Abstract Purpose of Review The goal of this review is to summarize the state of big data
analyses in the study of heart failure (HF). We discuss the use of big data in the HF space …

Next-generation sequencing and proteomics of cerebrospinal fluid from COVID-19 patients with neurological manifestations

H Wang, Z Zhang, J Zhou, S Han, Z Kang… - Frontiers in …, 2021 - frontiersin.org
The SARS-CoV-2 and its variants are still hitting the world. Ever since the outbreak,
neurological involvements as headache, ageusia, and anosmia in COVID-19 patients have …