PSGL-1 is the best-studied selectin ligand and has become a posterchild of versatility in
leukocyte adhesion, inflammation and immunology. The direct involvement of PSGL-1 in T …

Parasites from genus Schistosoma currently infect more than 200 million people worldwide.
Infection with Schistosoma mansoni causes intestinal schistosomiasis with geographical …

CD34 is routinely used to identify and isolate human hematopoietic stem/progenitor cells
(HSPCs) for use clinically in bone marrow transplantation, but its function on these cells …

Hematopoietic stem/progenitor cell (HSPC) homing occurs via cell adhesion mediated by
spatiotemporally organized ligand-receptor interactions. Although molecules and biological …

Neural stem cell (NSC)-based therapies offer potential for neural repair in central nervous
system (CNS) inflammatory and degenerative disorders. Typically, these conditions present …

Conventional chemotherapy and radiation therapy are often insufficient in eliminating
cancer and are accompanied by severe side effects, due to a lack in the specificity of their …

Exosomes are tiny vesicles released by cells that carry communications to local and distant
locations. Emerging research has revealed the role played by integrins found on the surface …

Molecular‐level selectin‐cluster of differentiation 44 (CD44) interactions are far from clear
because of the complexity and diversity of CD44 glycosylation and isoforms expressed on …

Selectins are key to mediating interactions involved in cellular adhesion and migration,
underlying processes such as immune responses, metastasis, and transplantation. Selectins …

Selectins guide the traffic of activated T-cells through the blood stream by mediating their
tethering and rolling onto inflamed endothelium, in this way acting as beacons to help …