An adult mouse model has been elaborated for studies of experimental cholera (Vibrio
cholerae enterotoxin‐induced intestinal secretion) and protective antitoxic immunity in either …

The possibility of an autoimmune mechanism of pathogenesis in amyotrophic lateral
sclerosis has long been considered, but the evidence to support a conventional autoimmune …

Membrane lipids not only provide the structural framework of cellular membranes but also
influence protein functions in several different ways. In comparison to proteins, however …

Gangliosides are biologically important glycolipids widely distributed in vertebrate cells. An
important member of the ganglioside family is the monosialylganglioside GM1, which has …

We have conducted a preliminary study of the optimum conditions for a therapeutic effect of
ganglioside GM1 in Alzheimer''s disease. Five patients with the early onset form of …

Siglecs are cell surface receptors whose functions are tied to the binding of their sialoglycan
ligands. Recently, we developed an optimized liposome formulation and used it to …

G M1 ganglioside has been localized on the surfaces of myelinated, peripheral nerve fibres
by using immunofluorescence to detect cholera toxin receptors. Unfixed, mouse sciatic …

A transfer protein specific for glycolipids has been isolated from bovine brain. As judged by
sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis, the protein is 68% pure …

Purified rat brain Ca2+/calmodulin‐dependent protein kinase II (CaM‐kinase II) is stimulated
by brain gangliosides to a level of about 30% the activity obtained in the presence of …

Vaccine antigen-specific antibody-secreting cell (ASC) responses in peripheral blood of
healthy adult volunteers were studied after oral immunization with a prototype …