COVID-19 and metabolic syndrome

H Dissanayake - Best Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
Convergence of the two pandemics: metabolic syndrome and COVID-19 over last two years
has posed unprecedented challenges to individuals as well as healthcare systems …

[HTML][HTML] Respiratory tract infections in diabetes–lessons from tuberculosis and influenza to guide understanding of COVID-19 severity

A Al-Sayyar, KD Hulme, R Thibaut, J Bayry… - Frontiers in …, 2022 - frontiersin.org
Patients with type-2 diabetes (T2D) are more likely to develop severe respiratory tract
infections. Such susceptibility has gained increasing attention since the global spread of …

[HTML][HTML] Systematic review and meta-analysis of statin use and mortality, intensive care unit admission and requirement for mechanical ventilation in COVID-19 …

US Lao, CF Law, DT Baptista-Hon… - Journal of Clinical …, 2022 - mdpi.com
There is mounting evidence that statin use is beneficial for COVID-19 outcomes. We
performed a systematic review and meta-analysis to evaluate the association between statin …

[HTML][HTML] Lipid compartments and lipid metabolism as therapeutic targets against coronavirus

D Cesar-Silva, FS Pereira-Dutra, ALM Giannini… - Frontiers in …, 2023 - frontiersin.org
Lipids perform a series of cellular functions, establishing cell and organelles' boundaries,
organizing signaling platforms, and creating compartments where specific reactions occur …

[HTML][HTML] Angiotensin-converting enzyme inhibitor and angiotensin receptor blocker use associated with reduced mortality and other disease outcomes in US veterans …

JG Rizk, C Wenziger, D Tran, L Hashemi, H Moradi… - Drugs, 2022 - Springer
Objective To determine the association between angiotensin-converting enzyme inhibitors
(ACEIs) or angiotensin II receptor blockers (ARBs) use and coronavirus disease 2019 …

Neutrophil extracellular traps (NETs): An emerging therapeutic target to improve infectious diseases outcomes

A Meier, G Sakoulas, V Nizet… - The Journal of Infectious …, 2024 - academic.oup.com
Neutrophils possess a diverse repertoire of pathogen clearance mechanisms, one of which
is the formation of neutrophil extracellular traps (NETs). NETs are complexes of histone …

Discontinuation of atorvastatin use in hospital is associated with increased risk of mortality in COVID‐19 patients

L Andrews, L Goldin, Y Shen, K Korwek… - Journal of Hospital …, 2022 - Wiley Online Library
Background Statins are a commonly used class of drugs, and reports have suggested that
their use may affect COVID‐19 disease severity and mortality risk. Objective The purpose of …

[HTML][HTML] Potential role of geranylgeraniol in managing statin-associated muscle symptoms: a COVID-19 related perspective

B Tan, KY Chin - Frontiers in Physiology, 2023 - frontiersin.org
Myopathy is the most common side effect of statins, but it has not been addressed effectively.
In anticipation of its wider use as a small molecule to complement the current COVID-19 …

[HTML][HTML] COVID-19 and lipids. The role of lipid disorders and statin use in the prognosis of patients with SARS-CoV-2 infection

S Surma, M Banach, J Lewek - Lipids in health and disease, 2021 - Springer
The global coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2
coronavirus started in March 2020. The conclusions from numerous studies indicate that …

[HTML][HTML] Statins use in patients with cardiovascular diseases and COVID-19 Outcomes: an Italian population-based cohort study

IC Antonazzo, C Fornari, D Rozza, S Conti… - Journal of Clinical …, 2022 - mdpi.com
Background: The role of statins among patients with established cardiovascular diseases
(CVDs) who are hospitalized with COVID-19 is still debated. This study aimed at assessing …