The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness

J Firth, N Siddiqi, AI Koyanagi, D Siskind… - The Lancet …, 2019 - thelancet.com
Background The poor physical health of people with mental illness is a multifaceted,
transdiagnostic, and global problem. People with mental illness have an increased risk of …

[HTML][HTML] Impact of psychotropic medication effects on obesity and the metabolic syndrome in people with serious mental illness

V Mazereel, J Detraux, D Vancampfort… - Frontiers in …, 2020 - frontiersin.org
People with serious mental illness (SMI), including schizophrenia, bipolar disorder, and
major depressive disorder, have a higher mortality rate and shortened life expectancy. This …

[HTML][HTML] Association between mental illness and COVID-19 susceptibility and clinical outcomes in South Korea: a nationwide cohort study

SW Lee, JM Yang, SY Moon, IK Yoo, EK Ha… - The Lancet …, 2020 - thelancet.com
Background Evidence for the associations between mental illness and the likelihood of a
positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test result and the …

The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies

W Marx, AJ McGuinness, T Rocks, A Ruusunen… - Molecular …, 2021 - nature.com
The importance of tryptophan as a precursor for neuroactive compounds has long been
acknowledged. The metabolism of tryptophan along the kynurenine pathway and its …

Effect of ultra-processed diet on gut microbiota and thus its role in neurodegenerative diseases

EEM Leo, MRS Campos - Nutrition, 2020 - Elsevier
The current dietary pattern is characterized by high consumption of ultra-processed foods
and lower consumption of fiber and vegetables, environmental factors that are associated …

Disparities in screening and treatment of cardiovascular diseases in patients with mental disorders across the world: systematic review and meta-analysis of 47 …

M Solmi, J Fiedorowicz, L Poddighe… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: This study used meta-analysis to assess disparities in cardiovascular disease
(CVD) screening and treatment in people with mental disorders, a group that has elevated …

The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta‐review of meta‐analyses of randomized controlled trials

J Firth, SB Teasdale, K Allott, D Siskind… - World …, 2019 - Wiley Online Library
The role of nutrition in mental health is becoming increasingly acknowledged. Along with
dietary intake, nutrition can also be obtained from “nutrient supplements”, such as …

Sex differences in schizophrenia relevant to clinical care

MV Seeman - Expert review of neurotherapeutics, 2021 - Taylor & Francis
Introduction: Most medical diagnoses present somewhat differently in men and women,
more so at specific periods of life. Treatment effects may also differ. This is true for …

Dysregulation of synaptic pruning as a possible link between intestinal microbiota dysbiosis and neuropsychiatric disorders

A Eltokhi, IE Janmaat, M Genedi… - Journal of …, 2020 - Wiley Online Library
The prenatal and early postnatal stages represent a critical time window for human brain
development. Interestingly, this window partly overlaps with the maturation of the intestinal …

Pharmacological management of glucose dysregulation in patients treated with second-generation antipsychotics

S Cernea, L Dima, CU Correll, P Manu - Drugs, 2020 - Springer
Fasting hyperglycemia, impaired glucose tolerance, prediabetes, and diabetes are
frequently present in patients treated with second-generation antipsychotics (SGAPs) for …