In recent years, a growing understanding of the underlying mechanisms of autoinflammatory
and autoimmune disease has enabled significant advances in biomaterial therapeutics for …

Abstract Purpose of Review Type 1 interferons (IFN-I) are of increasing interest across a
wide range of autoimmune rheumatic diseases. Historically, research into their role in …

Circulating cell-free DNA (cf-DNA) is released from dead and/or apoptotic leukocytes and
due to neutrophil extracellular traps contributing to an inflammatory response. Previous …

The immune system and autophagy share a functional relationship. Both innate and
adaptive immune responses involve autophagy and, depending on the disease's origin and …

Inflammatory processes and cancer stem cells (CSCs) are increasingly recognized as
factors in the development of tumors. Emerging evidence indicates that CSCs are …

Cell-free DNA (cfDNA) in human blood serum, urine, and other body fluids recently became
a commonly used diagnostic marker associated with various pathologies. This is because …

Hepatocellular carcinoma (HCC), the fifth most common kind of cancer in the world, is a
significant public health concern in Egypt. The development of HCC has been linked to …

Cells can release their DNA into the extracellular space and circulation by active
mechanisms or as a product of cell death. In oncology, this cell-free DNA (cfDNA) has …

Lung cancer is the leading cause of cancer-related deaths in Denmark. Novel diagnostic
and prognostic biomarkers may aid in early detection of this malignancy and improve …

cfDNA is known to be a beneficial biomarker for the diagnosis, treatment response, and
prognosis of sepsis. Previous cell line studies have shown that cfDNA in septic mice triggers …