Development of an anisotropically organized brain dECM hydrogel-based 3D neuronal culture platform for recapitulating the brain microenvironment in vivo

Y Seo, S Jeong, JJ Chung, SH Kim… - … Science & Engineering, 2019 - ACS Publications
To mimic the brain tissue microenvironment in vitro, the biological and structural properties
of the utilized system must be similar to those of the native brain in the microenvironment in …

Ultrasonic cavitation to prepare ECM hydrogels

GS Hussey, DG Nascari, LT Saldin, B Kolich, YC Lee… - Acta biomaterialia, 2020 - Elsevier
Hydrogels composed of extracellular matrix (ECM) have been used as a substrate for 3D
organoid culture, and in numerous preclinical and clinical applications to facilitate repair and …

Solubilized matrix derived from decellularized liver as a growth factor-immobilizable scaffold for hepatocyte culture

S Nakamura, H Ijima - Journal of bioscience and bioengineering, 2013 - Elsevier
Tissue engineering requires growth factors, cells and a scaffold to permit effective tissue
regeneration. This study focused on the development of a scaffold for liver tissue …

Design of experiments approach to engineer cell-secreted matrices for directing osteogenic differentiation

ML Decaris, JK Leach - Annals of biomedical engineering, 2011 - Springer
The presentation of extracellular matrix (ECM) proteins provides an opportunity to instruct
the phenotype and behavior of responsive cells. Decellularized cell-secreted matrix coatings …

Stem cell therapy combined with controlled release of growth factors for the treatment of sphincter dysfunction

S Shan, Q Li, T Criswell, A Atala, Y Zhang - Cell & Bioscience, 2023 - Springer
Sphincter dysfunction often occurs at the end of tubule organs such as the urethra, anus, or
gastroesophageal sphincters. It is the primary consequence of neuromuscular impairment …

[HTML][HTML] Combination of a human articular cartilage-derived extracellular matrix scaffold and microfracture techniques for cartilage regeneration: A proof of concept in a …

L Peng, H Li, H Deng, T Gao, R Li, Z Xu, Q Tian… - Journal of Orthopaedic …, 2024 - Elsevier
Background The utilization of decellularized extracellular matrix has gained considerable
attention across numerous areas in regenerative research. Of particular interest is the …

Bioprinting of stem cells: Interplay of bioprinting process, bioinks, and stem cell properties

S Ding, L Feng, J Wu, F Zhu, Z Tan… - … Biomaterials Science & …, 2018 - ACS Publications
Combining the advantages of 3D bioprinting technology and biological characteristics of
stem cells, bioprinting of stem cells is recognized as a novel technology with broad …

[HTML][HTML] A combined physicochemical approach towards human tenocyte phenotype maintenance

CNM Ryan, E Pugliese, N Shologu, D Gaspar… - Materials Today Bio, 2021 - Elsevier
During in vitro culture, bereft of their optimal tissue context, tenocytes lose their phenotype
and function. Considering that tenocytes in their native tissue milieu are exposed …

Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells

D Sun, Y Liu, H Wang, F Deng, Y Zhang, S Zhao… - International journal of …, 2018 - Elsevier
Developing reliable three-dimensional (3D) cell culture systems that can mimic native tumor
microenvironments is necessary for investigating the mechanism of hepatocellular …

Avoiding detrimental human immune response against Mammalian extracellular matrix implants

U Galili - Tissue Engineering Part B: Reviews, 2015 - liebertpub.com
This review describes the antibodies formed against mammalian extracellular matrix (ECM)
implants in humans and proposes methods for avoiding the detrimental effects of these …