Nanotechnology‐facilitated vaccine development during the coronavirus disease 2019 (COVID‐19) pandemic

Z Wang, K Cui, U Costabel, X Zhang - Exploration, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) continually poses a significant threat to the
human race, and prophylactic vaccination is the most potent approach to end this pandemic …

[HTML][HTML] Respiratory syncytial virus vaccines: a review of the candidates and the approved vaccines

X Topalidou, AM Kalergis, G Papazisis - Pathogens, 2023 - mdpi.com
Respiratory syncytial virus (RSV) is responsible for a significant proportion of global
morbidity and mortality affecting young children and older adults. In the aftermath of formalin …

Lessons from acquired natural immunity and clinical trials to inform next-generation human cytomegalovirus vaccine development

X Hu, HY Wang, CE Otero, JA Jenks… - Annual review of …, 2022 - annualreviews.org
Human cytomegalovirus (HCMV) infection, the most common cause of congenital disease
globally, affecting an estimated 1 million newborns annually, can result in lifelong sequelae …

Glycosylation shapes the efficacy and safety of diverse protein, gene and cell therapies

F Rocamora, AG Peralta, S Shin, J Sorrentino… - Biotechnology …, 2023 - Elsevier
Over recent decades, therapeutic proteins have had widespread success in treating a
myriad of diseases. Glycosylation, a near universal feature of this class of drugs, is a critical …

Capacity building for vaccine manufacturing across developing countries: the way forward

G Kumraj, S Pathak, S Shah, P Majumder… - Human Vaccines & …, 2022 - Taylor & Francis
Approved vaccines prevent 2 to 3 million deaths per year. There is a lack of equitable
access to vaccines in the low-and middle-income developing nations. Challenges in the life …

[HTML][HTML] The next-generation DNA vaccine platforms and delivery systems: Advances, challenges and prospects

B Lu, JM Lim, B Yu, S Song, P Neeli… - Frontiers in …, 2024 - frontiersin.org
Vaccines have proven effective in the treatment and prevention of numerous diseases.
However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such …

[PDF][PDF] Intranasal immunization with an RBD-hemagglutinin fusion protein harnesses preexisting immunity to enhance antigen-specific responses

A Kawai, N Tokunoh, E Kawahara… - The Journal of …, 2023 - Am Soc Clin Investig
Intranasal vaccines are anticipated to be powerful tools for combating many infectious
diseases, including SARS-CoV-2, because they induce not only systemic immunity but also …

Safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine

E Underwood, LM Dunkle, SA Madhi… - Expert Review of …, 2023 - Taylor & Francis
Introduction The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in significant morbidity and …

[HTML][HTML] Developments in rabies vaccines: the path traversed from Pasteur to the modern era of immunization

K Natesan, S Isloor, B Vinayagamurthy… - Vaccines, 2023 - mdpi.com
Rabies is a disease of antiquity and has a history spanning millennia ever since the first
interactions between humans and dogs. The alarming fatalities caused by this disease have …

[HTML][HTML] Nasal nanovaccines for SARS-CoV-2 to address COVID-19

J Huang, Y Ding, J Yao, M Zhang, Y Zhang, Z Xie… - Vaccines, 2022 - mdpi.com
COVID-19 is still prevalent around the globe. Although some SARS-CoV-2 vaccines have
been distributed to the population, the shortcomings of vaccines and the continuous …