The gut-lung axis in health and respiratory diseases: a place for inter-organ and inter-kingdom crosstalks

R Enaud, R Prevel, E Ciarlo, F Beaufils… - Frontiers in cellular …, 2020 - frontiersin.org
The gut and lungs are anatomically distinct, but potential anatomic communications and
complex pathways involving their respective microbiota have reinforced the existence of a …

The influence of the microbiome on respiratory health

TP Wypych, LC Wickramasinghe, BJ Marsland - Nature immunology, 2019 - nature.com
The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …

The role of lung and gut microbiota in the pathology of asthma

W Barcik, RCT Boutin, M Sokolowska, BB Finlay - Immunity, 2020 - cell.com
Asthma is a common chronic respiratory disease affecting more than 300 million people
worldwide. Clinical features of asthma and its immunological and molecular etiology vary …

Dysbiosis of the gut and lung microbiome has a role in asthma

K Hufnagl, I Pali-Schöll, F Roth-Walter… - Seminars in …, 2020 - Springer
Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …

Smoking and microbiome in oral, airway, gut and some systemic diseases

C Huang, G Shi - Journal of translational medicine, 2019 - Springer
The human microbiome harbors a diverse array of microbes which establishes a mutually
beneficial relation with the host in healthy conditions, however, the dynamic homeostasis is …

Neutrophilic inflammation in asthma and association with disease severity

A Ray, JK Kolls - Trends in immunology, 2017 - cell.com
Asthma is a chronic inflammatory disorder of the airways. While the local infiltration of
eosinophils and mast cells, and their role in the disease have long been recognized …

Food allergy

H Renz, KJ Allen, SH Sicherer, HA Sampson… - Nature reviews Disease …, 2018 - nature.com
Food allergies manifest in a variety of clinical conditions within the gastrointestinal tract, skin
and lungs, with the most dramatic and sometimes fatal manifestation being anaphylactic …

The microbiome and the respiratory tract

RP Dickson, JR Erb-Downward… - Annual review of …, 2016 - annualreviews.org
Although the notion that “the normal lung is free from bacteria” remains common in
textbooks, it is virtually always stated without citation or argument. The lungs are constantly …

Mechanisms and therapeutic strategies for non‐T2 asthma

E Sze, A Bhalla, P Nair - Allergy, 2020 - Wiley Online Library
Non‐T2 asthma is traditionally defined as asthma without features of T2 asthma. The
definition is arbitrary and is generally based on the presence of neutrophils in sputum, or the …

Revisiting T ype 2‐high and T ype 2‐low airway inflammation in asthma: current knowledge and therapeutic implications

D Robinson, M Humbert, R Buhl… - Clinical & …, 2017 - Wiley Online Library
Asthma is a complex respiratory disorder characterized by marked heterogeneity in
individual patient disease triggers and response to therapy. Several asthma phenotypes …