In the haematopoietic system, the principal function of erythropoietin (Epo) is the regulation
of red blood cell production, mediated by its specific cell surface receptor (EpoR). Following …

Multi-tissue erythropoietin receptor (EPO-R) expression provides for erythropoietin (EPO)
activity beyond its known regulation of red blood cell production. This review highlights the …

The growth factor erythropoietin (EPO) and erythropoietin receptors (EPOR) are expressed
in the nervous system. Neuronal expression of EPO and EPOR peaks during brain …

Erythropoietin (EPO), originally discovered as hematopoietic growth factor, has direct effects
on cells of the nervous system that make it a highly attractive candidate drug for …

The primary function of the glycoprotein hormone erythropoietin (Epo) is to promote red cell
production by inhibiting apoptosis of erythrocytic progenitors in hemopoietic tissues …

Purpose: To provide an overview of the current knowledge on neuroprotective properties of
Erythropoietin (Epo), mechanisms by which Epo produces neuroprotection, and signaling …

The tissue protective functions of the hematopoietic growth factor erythropoietin (EPO) are
independent of its action on erythropoiesis. EPO and its receptors (EPOR) are expressed in …

Background. Erythropoietin (EPO) is neuroprotective in experimental models of stroke and
subarachnoid haemorrhage (SAH) and possibly in patients with thromboembolic stroke. We …

Background Huntington's disease (HD) is a hereditary neurodegenerative disorder caused
by an expanded CAG repeat in the HD gene. Both excitotoxicity and oxidative stress have …

Acute stroke is one of the major causes of death and disabilities. Since the 1980s many
clinical studies have been conducted to evaluate neuroprotective approaches to treat this …