Pathogenesis of preterm birth: bidirectional inflammation in mother and fetus
ES Green, PC Arck - Seminars in immunopathology, 2020 - Springer
Abstract Preterm birth (PTB) complicates 5–18% of pregnancies globally and is a leading
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …
Insight into TLR4-mediated immunomodulation in normal pregnancy and related disorders
Unlike organ transplants where an immunosuppressive environment is required, a
successful pregnancy involves an extremely robust, dynamic, and responsive maternal …
successful pregnancy involves an extremely robust, dynamic, and responsive maternal …
Deciphering the endometrial niche of human thin endometrium at single-cell resolution
H Lv, G Zhao, P Jiang, H Wang… - Proceedings of the …, 2022 - National Acad Sciences
Thin endometrium has been widely recognized as a critical cause of infertility, recurrent
pregnancy loss, and placental abnormalities; however, access to effective treatment is a …
pregnancy loss, and placental abnormalities; however, access to effective treatment is a …
Regulatory T cells play a role in a subset of idiopathic preterm labor/birth and adverse neonatal outcomes
Regulatory T cells (Tregs) have been exhaustively investigated during early pregnancy;
however, their role later in gestation is poorly understood. Herein, we report that functional …
however, their role later in gestation is poorly understood. Herein, we report that functional …
Single‐cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion
Objectives Successful pregnancy involves the homeostasis between maternal decidua and
fetoplacental units, whose disruption contributes to compromised pregnancy outcomes …
fetoplacental units, whose disruption contributes to compromised pregnancy outcomes …
Spontaneous preterm birth: Involvement of multiple feto-maternal tissues and organ systems, differing mechanisms, and pathways
MS Vidal Jr, RCV Lintao, MEL Severino… - Frontiers in …, 2022 - frontiersin.org
Survivors of preterm birth struggle with multitudes of disabilities due to improper in utero
programming of various tissues and organ systems contributing to adult-onset diseases at a …
programming of various tissues and organ systems contributing to adult-onset diseases at a …
Perinatal infection, inflammation, preterm birth, and brain injury: A review with proposals for future investigations
JD Reiss, LS Peterson, SN Nesamoney, AL Chang… - Experimental …, 2022 - Elsevier
Preterm newborns are exposed to several risk factors for developing brain injury. Clinical
studies have suggested that the presence of intrauterine infection is a consistent risk factor …
studies have suggested that the presence of intrauterine infection is a consistent risk factor …
[HTML][HTML] Glycerol monolaurate improves intestinal morphology and antioxidant status by suppressing inflammatory responses and nuclear factor kappa-B signaling in …
L Kong, Y Cai, X Pan, C Xiao, Z Song - Animal Nutrition, 2023 - Elsevier
Medium-chain fatty acids and their derivatives are natural ingredients that support
immunological functions in animals. The effects of glycerol monolaurate (GML) on intestinal …
immunological functions in animals. The effects of glycerol monolaurate (GML) on intestinal …
Intrauterine infusion of human platelet-rich plasma improves endometrial regeneration and pregnancy outcomes in a murine model of Asherman's syndrome
Asherman's syndrome (AS) is characterized by intrauterine adhesion or fibrosis resulting
from damage to the endometrium, often leading to amenorrhea, infertility, or recurrent …
from damage to the endometrium, often leading to amenorrhea, infertility, or recurrent …
Primary decidual zone formation requires Scribble for pregnancy success in mice
J Yuan, S Aikawa, W Deng, A Bartos, G Walz… - Nature …, 2019 - nature.com
Scribble (Scrib) is a scaffold protein with multifunctional roles in PCP, tight junction and
Hippo signaling. This study shows that Scrib is expressed in stromal cells around the …
Hippo signaling. This study shows that Scrib is expressed in stromal cells around the …