Chondroitin sulfate (CS) is an important extracellular matrix component of mineralized
tissues. It participates in biomineralization, osteoblast differentiation and promotes bone …

Some biomolecules involved in pathological calcification have been identified. However, the
exact mechanism in which this intricate process occurs remains unknown. Extracellular DNA …

In bony vertebrates, skeletal mineralization relies on the secretory calcium-binding
phosphoproteins (Scpp) family whose members are acidic extracellular proteins …

The peri-tooth root alveolar loss often does not have sufficient space for repair material
transplantation and plasticity. Mesenchymal stem cell (MSC) sheets have an advantage in …

Osteoporosis is a major health problem in postmenopausal women. Herein we evaluated
the effects of 12-week tocotrienols (TT) supplementation on serum metabolites in …

Understanding the molecular mechanism by which the periodontal ligament (PDL) is
maintained uncalcified between two mineralized tissues (cementum and bone) may facilitate …

Human periodontal ligament cells (PDLCs) play an important role in periodontal tissue
stabilization and function. In the process of osteogenic differentiation of PDLSCs, the …

Interfacial failure at the resin-dentin interface is a significant disadvantage of resin-based
dental restoration. In this study, we created bio-inspired bio-nano complexes using the …

While cartilage is an ancient tissue found both in protostomes and deuterostomes, its
mineralization evolved more recently, within the vertebrate lineage. SPARC, SPARC-L, and …

Teeth, scales, fin spines, and other odontodes are hot topics in evolutionary biology due to
their great variation in number, shape, and anatomical localization in vertebrates as a result …