Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment

Q Yang, M Ciebiera, MV Bariani, M Ali… - Endocrine …, 2022 - academic.oup.com
Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

[HTML][HTML] Menstruation: science and society

HOD Critchley, E Babayev, SE Bulun, S Clark… - American journal of …, 2020 - Elsevier
Women's health concerns are generally underrepresented in basic and translational
research, but reproductive health in particular has been hampered by a lack of …

Epidemiology and management of uterine fibroids

E Giuliani, S As‐Sanie, EE Marsh - International Journal of …, 2020 - Wiley Online Library
Uterine leiomyomas are one of the most common and yet understudied diseases in women.
These tumors, commonly known as fibroids, affect women mainly during their reproductive …

[HTML][HTML] Uterine bleeding: how understanding endometrial physiology underpins menstrual health

V Jain, RR Chodankar, JA Maybin… - Nature reviews …, 2022 - nature.com
Menstruation is a physiological process that is typically uncomplicated. However, up to one
third of women globally will be affected by abnormal uterine bleeding (AUB) at some point in …

[HTML][HTML] Progesterone actions and resistance in gynecological disorders

JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

Epidemiology and risk factors of uterine fibroids

D Pavone, S Clemenza, F Sorbi, M Fambrini… - Best practice & research …, 2018 - Elsevier
Risk factors, both modifiable and non-modifiable, are associated with the development of
fibroids. These include age, race, endogenous and exogenous hormonal factors, obesity …

Uterine fibroids

EA Stewart, SK Laughlin-Tommaso… - Nature reviews Disease …, 2016 - nature.com
Uterine fibroids (also known as leiomyomas or myomas) are common clonal neoplasms of
the uterus. Fibroids have both smooth muscle and fibroblast components, in addition to a …

Adenomyosis pathogenesis: insights from next-generation sequencing

SE Bulun, S Yildiz, M Adli, JJ Wei - Human Reproduction Update, 2021 - academic.oup.com
BACKGROUND Adenomyosis, characterized by the presence of islands of endometrial
tissue surrounded by hypertrophic smooth muscle cells within the myometrium, is one of the …

[HTML][HTML] Uterine fibroids: diagnosis and treatment

MSD De La Cruz, EM Buchanan - American family physician, 2017 - aafp.org
Uterine fibroids are common benign neoplasms, with a higher prevalence in older women
and in those of African descent. Many are discovered incidentally on clinical examination or …

[HTML][HTML] Epidemiology of uterine myomas: a review

R Sparic, L Mirkovic, A Malvasi… - International journal of …, 2016 - ncbi.nlm.nih.gov
Myomas are the most common benign tumors of the genital organs in women of
childbearing age, causing significant morbidity and impairing their quality of life. In our …