Immune interaction between SARS-CoV-2 and Mycobacterium tuberculosis

P Booysen, KA Wilkinson, D Sheerin, R Waters… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2 and Mycobacterium tuberculosis (Mtb) are major infectious causes of death,
with meta-analyses and population-based studies finding increased mortality in co-infected …

Tuberculosis and COVID-19 in the elderly: factors driving a higher burden of disease

A Allué-Guardia, JB Torrelles, A Sigal - Frontiers in Immunology, 2023 - frontiersin.org
Mycobacterium tuberculosis (M. tb) and SARS-CoV-2 are both infections that can lead to
severe disease in the lower lung. However, these two infections are caused by very different …

[HTML][HTML] Clinical manifestations of active tuberculosis patients coinfected with severe acute respiratory syndrome coronavirus-2

G Habib, K Mahmood, L Ahmad, H Gul, A Hayat… - Journal of Clinical …, 2023 - Elsevier
Abstract Summary background The coronavirus 2019 pandemic was caused by a new
single-strand RNA virus that originated from Wuhan, China, and infected more than 190 …

Protective interplay: Mycobacterium tuberculosis diminishes SARS-CoV-2 severity through innate immune priming

BD Williams, D Ferede, HFM Abdelaal… - Frontiers in …, 2024 - frontiersin.org
At the beginning of the COVID-19 pandemic those with underlying chronic lung conditions,
including tuberculosis (TB), were hypothesized to be at higher risk of severe COVID-19 …

Clinical characteristics and outcomes of patients with COVID-19 and tuberculosis coinfection

J Lv, M Liang, L Wang, M Zhang, R Liu, H Liang… - Infectious …, 2023 - Taylor & Francis
Background Data on the coincidence of Tuberculosis (TB) and Coronavirus disease 2019
(COVID-19) are limited. We sought to investigate the clinical characteristics and outcomes of …

[HTML][HTML] Changes in the incidence, clinical features and outcomes of tuberculosis during COVID-19 pandemic

KPF Chan, M Ting-Fung, S Sridhar, MMS Lui… - Journal of Infection and …, 2024 - Elsevier
Background COVID-19 pandemic has disrupted tuberculosis (TB) services in many
countries, but the impacts on sites of involvement, drug susceptibility, smear positivity and …

Antifungal, Antimycobacterial, Protease and α‒Amylase Inhibitory Activities of a Novel Serine Bifunctional Protease Inhibitor from Adenanthera pavonina L. Seeds

R da Silva Gebara, MS da Silva, SD Calixto… - Probiotics and …, 2023 - Springer
Antifungal resistance poses a significant challenge to disease management, necessitating
the development of novel drugs. Antimicrobial peptides offer potential solutions. This study …

Spatio‐Temporal Pattern of Tuberculosis Distribution in Romania and Particulate Matter Pollution Associated With Risk of Infection

D Peptenatu, AM Băloi, O Andronic, A Bolocan… - …, 2024 - Wiley Online Library
The study proposes a dynamic spatio‐temporal profile of the distribution of tuberculosis
incidence and air pollution in Romania, where this infectious disease induces more than …

Synthesis and Biological Activity of Piperidinothiosemicarbazones Derived from Aminoazinecarbonitriles

D Ziembicka, K Gobis, M Szczesio… - Pharmaceuticals, 2023 - mdpi.com
To investigate how structural modifications affect tuberculostatic potency, we synthesized
seven new piperidinothiosemicrabazone derivatives 8–14, in which three of them had a …

Colliding Challenges: An Analysis of SARS-CoV-2 Infection in Patients with Pulmonary Tuberculosis versus SARS-CoV-2 Infection Alone

C Mihuta, A Socaci, P Hogea, E Tudorache, MS Mihuta… - Medicina, 2024 - mdpi.com
Background and Objectives: The concurrent occurrence of tuberculosis and COVID-19
coinfection poses significant clinical complexities, warranting a nuanced approach to …