Blood biomarkers and structural imaging correlations post-traumatic brain injury: a systematic review

DP Whitehouse, AR Vile, K Adatia, R Herlekar… - …, 2022 - journals.lww.com
BACKGROUND: Blood biomarkers are of increasing importance in the diagnosis and
assessment of traumatic brain injury (TBI). However, the relationship between them and …

A decade of mTBI experience: what have we learned? A summary of proceedings from a NATO lecture series on military mTBI

KE Robinson-Freeman, KL Collins, B Garber… - Frontiers in …, 2020 - frontiersin.org
Mild traumatic brain injury (mTBI, also known as a concussion) as a consequence of
battlefield blast exposure or blunt force trauma has been of increasing concern to militaries …

Serial measurements of serum glial fibrillary acidic protein in moderate-severe traumatic brain injury: potential utility in providing insights into secondary insults and …

CS Robertson, FS Martinez, LE McQuillan… - Journal of …, 2024 - liebertpub.com
In patients with traumatic brain injury (TBI), serum biomarkers may have utility in assessing
the evolution of secondary brain injury. A panel of nine brain-injury-associated biomarkers …

Developing a cognition endpoint for traumatic brain injury clinical trials

ND Silverberg, PK Crane, K Dams-O'Connor… - Journal of …, 2017 - liebertpub.com
Cognitive impairment is a core clinical feature of traumatic brain injury (TBI). After TBI,
cognition is a key determinant of post-injury productivity, outcome, and quality of life. As a …

miRNA dysregulation in traumatic brain injury and epilepsy: A systematic review to identify putative biomarkers for post-traumatic epilepsy

P Kumar - Metabolic Brain Disease, 2023 - Springer
Traumatic brain injury (TBI) leads to post-traumatic epilepsy (PTE); hence, both TBI and PTE
share various similar molecular mechanisms. MicroRNA (miRNA) is a small noncoding RNA …

diagnostic utility of glial fibrillary acidic protein beyond 12 hours after traumatic brain injury: A TRACK-TBI study

AM Puccio, JK Yue, FK Korley, DO Okonkwo… - Journal of …, 2024 - liebertpub.com
Blood levels of glial fibrillary acidic protein (GFAP) and ubiquitin carboxyl-terminal hydrolase-
L1 (UCH-L1) within 12h of suspected traumatic brain injury (TBI) have been approved by the …

Elevated markers of brain injury as a result of clinically asymptomatic high-acceleration head impacts in high-school football athletes

JR Joseph, JS Swallow, K Willsey, AP Lapointe… - Journal of …, 2018 - thejns.org
OBJECTIVE This prospective observational cohort study of high-school football athletes was
performed to determine if high-acceleration head impacts (HHIs) that do not result in …

Post-traumatic headache and mild traumatic brain injury: brain networks and connectivity

N Maleki, A Finkel, G Cai, A Ross, RD Moore… - Current Pain and …, 2021 - Springer
Abstract Purpose of Review Post-traumatic headache (PTH) consequent to mild traumatic
brain injury (mTBI) is a complex, multidimensional, chronic neurological disorder. The …

Biomarkers and acute brain injuries: interest and limits

S Mrozek, J Dumurgier, G Citerio, A Mebazaa… - Critical Care, 2014 - Springer
For patients presenting with acute brain injury (such as traumatic brain injury, subarachnoid
haemorrhage and stroke), the diagnosis and identification of intracerebral lesions and …

Plasma osteopontin may predict neuroinflammation and the severity of pediatric traumatic brain injury

N Gao, X Zhang-Brotzge, B Wali… - Journal of Cerebral …, 2020 - journals.sagepub.com
Traumatic brain injury (TBI) is the leading cause of death in children and adolescents in
developed countries, but there are no blood-based biomarkers to support the diagnosis or …