▪ Abstract Interrogation of tissue with light offers the potential for noninvasive chemical
measurement, and penetration with near-infrared wavelengths (750–1000 nm) is greater …

The non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist ketamine can block
the action of excitotoxic amino acids in the central nervous system. S (+) ketamine has a 2–3 …

Surface fluorescence spectroscopy of the beating heart to measure cytosolic calcium has
been limited by the need to use ultraviolet excitation light for many of the commonly used …

Objective: Increased microvascular permeability and perfusion mismatch are hallmarks of
sepsis or septic shock. The intestinal mucosa is very sensitive to tissue hypoxia. Intestinal …

Objective: Disturbances of intestinal microcirculation associated with sepsis and septic
shock result in diminished mucosal oxygenation. Tissue hypoxia as well as mediator …

The invention provides a method for determining a concentration of a substance in a
compartment comprising exciting an endogenous compound, or a functional part, derivative …

Maintenance of adequate oxygen delivery (DO 2) to the tissue cells can be considered a
primary objective in intensive care and peri-operative patient management. Generally, it is …

A rapid micro-lightguide spectrometer (EMPHO II) coupled to an automatic three axis
positioning system enables very precise and fast 2D-scans at the surface of human skin. The …

There is a clinical need to measure local tissue oxygen saturation (StO2), oxy-, deoxy-and
total haemoglobin concentration ([O2Hb],[HHb],[tHb]) in human tissue. The aim was to …

Millimeter-wave and THz spectroscopy is nowadays a huge research field largely focused
on the development of new and improved instruments and techniques for practical …