The mesenteric fat and intestinal muscle interface: creeping fat influencing stricture formation in Crohn's disease

R Mao, S Kurada, IO Gordon, ME Baker… - Inflammatory bowel …, 2019 - academic.oup.com
Adipose tissue is present in close proximity to various organs in the human body. One
prominent example is fat contained in the mesentery that is contiguous with all abdominal …

Nutrition and IBD: malnutrition and/or sarcopenia? A practical guide

F Scaldaferri, M Pizzoferrato… - Gastroenterology …, 2017 - Wiley Online Library
Malnutrition is a major complication of inflammatory bowel disease (IBD). This mini review is
focusing on main determinants of malnutrition in IBD, the most important components of …

Sarcopenia in inflammatory bowel disease: a narrative overview

A Dhaliwal, JI Quinlan, K Overthrow, C Greig, JM Lord… - Nutrients, 2021 - mdpi.com
Malnutrition is a common condition encountered in patients with inflammatory bowel disease
(IBD) and is often associated with sarcopenia (the reduction of muscle mass and strength) …

Extragastric Diseases and Helicobacter pylori

F Franceschi, A Gasbarrini, SA Polyzos… - …, 2015 - Wiley Online Library
The extragastric manifestations of Helicobacter pylori infection still remain a very strong topic
throughout the H. pylori world. Indeed, H. pylori may interfere with many biological …

Role of adipose tissue in inflammatory bowel disease

E Karaskova, M Velganova-Veghova, M Geryk… - International journal of …, 2021 - mdpi.com
Inflammatory bowel diseases (IBDs), chronic inflammatory disorders affecting the
gastrointestinal tract, include Crohn's disease and ulcerative colitis. There are increasing …

Pancreatic glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation

Y Kurashima, T Kigoshi, S Murasaki, F Arai… - Nature …, 2021 - nature.com
Increases in adhesive and invasive commensal bacteria, such as Escherichia coli, and
subsequent disruption of the epithelial barrier is implicated in the pathogenesis of …

Pathogenesis of fibrostenosing Crohn's disease

J Li, R Mao, S Kurada, J Wang, S Lin, J Chandra… - Translational …, 2019 - Elsevier
Crohn's disease (CD) is a chronic inflammatory disease, which could affect any part of the
gastrointestinal tract. A severe complication of CD is fibrosis-associated strictures, which can …

The complex relationship between microbiota, immune response and creeping fat in Crohn's disease

R Suau, E Pardina, E Domènech… - Journal of Crohn's …, 2022 - academic.oup.com
In the last decade, there has been growing interest in the pathological involvement of
hypertrophic mesenteric fat attached to the serosa of the inflamed intestinal segments …

Impact of obesity on the course of management of inflammatory bowel disease—a review

A Michalak, B Kasztelan-Szczerbińska, H Cichoż-Lach - Nutrients, 2022 - mdpi.com
It is already well-known that visceral adipose tissue is inseparably related to the
pathogenesis, activity, and general outcome of inflammatory bowel disease (IBD). We are …

A CCL2+DPP4+ subset of mesenchymal stem cells expedites aberrant formation of creeping fat in humans

F Wu, F Wu, Q Zhou, X Liu, J Fei, D Zhang… - Nature …, 2023 - nature.com
Creeping fat is a typical feature of Crohn's disease. It refers to the expansion of mesenteric
adipose tissue around inflamed and fibrotic intestines and is associated with stricture …