Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review
N-heterocycles are important, not only because of their abundance, but above all because of
their chemical, biological and technical significance. They play an important role in …
their chemical, biological and technical significance. They play an important role in …
Forty years of molecular diagnostics for infectious diseases
JE Schmitz, CW Stratton, DH Persing… - Journal of Clinical …, 2022 - Am Soc Microbiol
Nearly 40 years have elapsed since the invention of the PCR, with its extremely sensitive
and specific ability to detect nucleic acids via in vitro enzyme-mediated amplification. In turn …
and specific ability to detect nucleic acids via in vitro enzyme-mediated amplification. In turn …
40 years after the registration of acyclovir: do we need new anti-herpetic drugs?
A Majewska, B Mlynarczyk-Bonikowska - International journal of …, 2022 - mdpi.com
Herpes simplex virus types 1 and 2 HSV1 and 2, namely varicella-zoster VZV and
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …
Progress and challenges in the prevention, diagnosis, and management of cytomegalovirus infection in transplantation
Hosts with compromised or naive immune systems, such as individuals living with HIV/AIDS,
transplant recipients, and fetuses, are at the highest risk for complications from …
transplant recipients, and fetuses, are at the highest risk for complications from …
Drug resistance assessed in a phase 3 clinical trial of maribavir therapy for refractory or resistant cytomegalovirus infection in transplant recipients
S Chou, S Alain, C Cervera, RF Chemaly… - The Journal of …, 2024 - academic.oup.com
Background This drug resistance analysis of a randomized trial includes 234 patients
receiving maribavir and 116 receiving investigator-assigned standard therapy (IAT), where …
receiving maribavir and 116 receiving investigator-assigned standard therapy (IAT), where …
Insects, rodents, and pets as reservoirs, vectors, and sentinels of antimicrobial resistance
This paper reviews the occurrence of antimicrobial resistance (AMR) in insects, rodents, and
pets. Insects (eg, houseflies, cockroaches), rodents (rats, mice), and pets (dogs, cats) act as …
pets. Insects (eg, houseflies, cockroaches), rodents (rats, mice), and pets (dogs, cats) act as …
Drug resistance mutations and associated phenotypes detected in clinical trials of maribavir for treatment of cytomegalovirus infection
S Chou, K Song, J Wu, T Bo… - The Journal of infectious …, 2022 - academic.oup.com
Background In separate phase 2 trials, 120 patients received maribavir for cytomegalovirus
(CMV) infection failing conventional therapy (trial 202) and 119 received maribavir for …
(CMV) infection failing conventional therapy (trial 202) and 119 received maribavir for …
Treatment for First Cytomegalovirus Infection Post–Hematopoietic Cell Transplant in the AURORA Trial: A Multicenter, Double-Blind, Randomized, Phase 3 Trial …
GA Papanicolaou, RK Avery… - Clinical Infectious …, 2024 - academic.oup.com
Background Neutropenia may limit the use of valganciclovir treatment for cytomegalovirus
(CMV) infection following hematopoietic cell transplant (HCT). A phase 2 study indicated …
(CMV) infection following hematopoietic cell transplant (HCT). A phase 2 study indicated …
Cytomegalovirus in the transplant setting: Where are we now and what happens next? A report from the International CMV Symposium 2021
CN Kotton, J Torre‐Cisneros… - Transplant Infectious …, 2022 - Wiley Online Library
Abstract The CMV Symposium in September 2021 was an international conference
dedicated to cytomegalovirus (CMV) infection after solid organ or hematopoietic stem cell …
dedicated to cytomegalovirus (CMV) infection after solid organ or hematopoietic stem cell …
[HTML][HTML] American Society for Transplantation and Cellular Therapy Series:# 4-Cytomegalovirus treatment and management of resistant or refractory infections after …
MK Yong, TL Shigle, YJ Kim, PA Carpenter… - … and Cellular Therapy, 2021 - Elsevier
Abstract The Practice Guidelines Committee of the American Society of Transplantation and
Cellular Therapy (ASTCT) partnered with its Transpl. Infect. Dis. Special Interest Group (TID …
Cellular Therapy (ASTCT) partnered with its Transpl. Infect. Dis. Special Interest Group (TID …