Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review

A Mermer, T Keles, Y Sirin - Bioorganic Chemistry, 2021 - Elsevier
N-heterocycles are important, not only because of their abundance, but above all because of
their chemical, biological and technical significance. They play an important role in …

Forty years of molecular diagnostics for infectious diseases

JE Schmitz, CW Stratton, DH Persing… - Journal of Clinical …, 2022 - Am Soc Microbiol
Nearly 40 years have elapsed since the invention of the PCR, with its extremely sensitive
and specific ability to detect nucleic acids via in vitro enzyme-mediated amplification. In turn …

40 years after the registration of acyclovir: do we need new anti-herpetic drugs?

A Majewska, B Mlynarczyk-Bonikowska - International journal of …, 2022 - mdpi.com
Herpes simplex virus types 1 and 2 HSV1 and 2, namely varicella-zoster VZV and
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …

Progress and challenges in the prevention, diagnosis, and management of cytomegalovirus infection in transplantation

AP Limaye, TM Babu, M Boeckh - Clinical Microbiology Reviews, 2020 - Am Soc Microbiol
Hosts with compromised or naive immune systems, such as individuals living with HIV/AIDS,
transplant recipients, and fetuses, are at the highest risk for complications from …

Drug resistance assessed in a phase 3 clinical trial of maribavir therapy for refractory or resistant cytomegalovirus infection in transplant recipients

S Chou, S Alain, C Cervera, RF Chemaly… - The Journal of …, 2024 - academic.oup.com
Background This drug resistance analysis of a randomized trial includes 234 patients
receiving maribavir and 116 receiving investigator-assigned standard therapy (IAT), where …

Insects, rodents, and pets as reservoirs, vectors, and sentinels of antimicrobial resistance

W Gwenzi, N Chaukura, N Muisa-Zikali, C Teta… - Antibiotics, 2021 - mdpi.com
This paper reviews the occurrence of antimicrobial resistance (AMR) in insects, rodents, and
pets. Insects (eg, houseflies, cockroaches), rodents (rats, mice), and pets (dogs, cats) act as …

Drug resistance mutations and associated phenotypes detected in clinical trials of maribavir for treatment of cytomegalovirus infection

S Chou, K Song, J Wu, T Bo… - The Journal of infectious …, 2022 - academic.oup.com
Background In separate phase 2 trials, 120 patients received maribavir for cytomegalovirus
(CMV) infection failing conventional therapy (trial 202) and 119 received maribavir for …

Treatment for First Cytomegalovirus Infection Post–Hematopoietic Cell Transplant in the AURORA Trial: A Multicenter, Double-Blind, Randomized, Phase 3 Trial …

GA Papanicolaou, RK Avery… - Clinical Infectious …, 2024 - academic.oup.com
Background Neutropenia may limit the use of valganciclovir treatment for cytomegalovirus
(CMV) infection following hematopoietic cell transplant (HCT). A phase 2 study indicated …

Cytomegalovirus in the transplant setting: Where are we now and what happens next? A report from the International CMV Symposium 2021

CN Kotton, J Torre‐Cisneros… - Transplant Infectious …, 2022 - Wiley Online Library
Abstract The CMV Symposium in September 2021 was an international conference
dedicated to cytomegalovirus (CMV) infection after solid organ or hematopoietic stem cell …

[HTML][HTML] American Society for Transplantation and Cellular Therapy Series:# 4-Cytomegalovirus treatment and management of resistant or refractory infections after …

MK Yong, TL Shigle, YJ Kim, PA Carpenter… - … and Cellular Therapy, 2021 - Elsevier
Abstract The Practice Guidelines Committee of the American Society of Transplantation and
Cellular Therapy (ASTCT) partnered with its Transpl. Infect. Dis. Special Interest Group (TID …