Layered double hydroxide-based nanomaterials for biomedical applications

T Hu, Z Gu, GR Williams, M Strimaite, J Zha… - Chemical Society …, 2022 - pubs.rsc.org
Against the backdrop of increased public health awareness, inorganic nanomaterials have
been widely explored as promising nanoagents for various kinds of biomedical applications …

Targeted drug delivery strategies for precision medicines

MT Manzari, Y Shamay, H Kiguchi, N Rosen… - Nature Reviews …, 2021 - nature.com
Progress in the field of precision medicine has changed the landscape of cancer therapy.
Precision medicine is propelled by technologies that enable molecular profiling, genomic …

A peritumorally injected immunomodulating adjuvant elicits robust and safe metalloimmunotherapy against solid tumors

L Zhang, J Zhao, X Hu, C Wang, Y Jia, C Zhu… - Advanced …, 2022 - Wiley Online Library
Clinical immunotherapy of solid tumors elicits durable responses only in a minority of
patients, largely due to the highly immunosuppressive tumor microenvironment (TME) …

Boosting the sonodynamic cancer therapy performance of 2D layered double hydroxide nanosheet‐based sonosensitizers via crystalline‐to‐amorphous phase …

T Hu, W Shen, F Meng, S Yang, S Yu, H Li… - Advanced …, 2023 - Wiley Online Library
Sonodynamic therapy (SDT) has been a promising therapeutic modality for cancer because
of its superior advantages compared with other therapeutic strategies. However, the current …

[HTML][HTML] Overcoming Cancer Multi-drug Resistance (MDR): Reasons, mechanisms, nanotherapeutic solutions, and challenges

C Duan, M Yu, J Xu, BY Li, Y Zhao… - Biomedicine & …, 2023 - Elsevier
Multi-drug resistance (MDR) in cancer cells, either intrinsic or acquired through various
mechanisms, significantly hinders the therapeutic efficacy of drugs. Typically, the reduced …

Efficient immunotherapy of drug-free layered double hydroxide nanoparticles via neutralizing excess acid and blocking tumor cell autophagy

L Zhang, Y Jia, J Yang, L Zhang, S Hou, X Niu, J Zhu… - ACS …, 2022 - ACS Publications
Cancer immunotherapy efficacy is largely limited by the suppressive tumor immune
microenvironment (TIME) where antitumor immune cells are inhibited and tumor antigens …

Nanoparticles: a new approach to upgrade cancer diagnosis and treatment

Z Yu, L Gao, K Chen, W Zhang, Q Zhang, Q Li… - Nanoscale Research …, 2021 - Springer
Traditional cancer therapeutics have been criticized due to various adverse effects and
insufficient damage to targeted tumors. The breakthrough of nanoparticles provides a novel …

Functionalized layered double hydroxides for innovative applications

M Laipan, J Yu, R Zhu, J Zhu, AT Smith, H He… - Materials …, 2020 - pubs.rsc.org
Two-dimensional layered double hydroxides (LDHs) are currently a topic of significant
interest due to their extraordinary physiochemical properties. LDHs are potentially useful in …

Advancement of cancer immunotherapy using nanoparticles-based nanomedicine

V Gowd, A Ahmad, M Tarique, M Suhail… - Seminars in cancer …, 2022 - Elsevier
Cancer has complex pathophysiology and is one of the primary causes of death and
morbidity across the world. Chemotherapy, targeted therapy, radiation therapy, and …

Recent developments in metallic nanomaterials for cancer therapy, diagnosing and imaging applications

DN Păduraru, D Ion, AG Niculescu, F Mușat… - Pharmaceutics, 2022 - mdpi.com
Cancer continues to represent a global health concern, imposing an ongoing need to
research for better treatment alternatives. In this context, nanomedicine seems to be the …