Pathogenesis of pneumonia and acute lung injury
ME Long, RK Mallampalli, JC Horowitz - Clinical Science, 2022 - portlandpress.com
Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …
and critical care healthcare professionals, and these challenges have recently garnered …
[HTML][HTML] Comorbid chronic diseases and acute organ injuries are strongly correlated with disease severity and mortality among COVID-19 patients: a systemic review …
The recent outbreak of COVID-19 has been rapidly spreading on a global scale. To date,
there is no specific vaccine against the causative virus, SARS-CoV-2, nor is there an …
there is no specific vaccine against the causative virus, SARS-CoV-2, nor is there an …
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 … - Nature, 2021 - nature.com
The genetic make-up of an individual contributes to the susceptibility and response to viral
infection. Although environmental, clinical and social factors have a role in the chance of …
infection. Although environmental, clinical and social factors have a role in the chance of …
Genetic ancestry effects on the response to viral infection are pervasive but cell type specific
Humans differ in their susceptibility to infectious disease, partly owing to variation in the
immune response after infection. We used single-cell RNA sequencing to quantify variation …
immune response after infection. We used single-cell RNA sequencing to quantify variation …
Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility
The COVID-19 pandemic has accounted for millions of infections and hundreds of thousand
deaths worldwide in a short-time period. The patients demonstrate a great diversity in …
deaths worldwide in a short-time period. The patients demonstrate a great diversity in …
Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity
K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …
claiming millions of lives and pushing healthcare systems in many countries to the brink …
Mapping the human genetic architecture of COVID-19: an update
COVID-19 Host Genetics Initiative, A Ganna - MedRxiv, 2021 - medrxiv.org
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic continues to pose a major
public health threat especially in countries with low vaccination rates. To better understand …
public health threat especially in countries with low vaccination rates. To better understand …
The Interferon-induced transmembrane protein 3 gene (IFITM3) rs12252 C variant is associated with COVID-19
J Gómez, GM Albaiceta, E Cuesta-Llavona… - Cytokine, 2021 - Elsevier
Background and aims The interferon-induced transmembrane proteins play an important
antiviral role by preventing viruses from traversing the cellular lipid bilayer. IFITM3 gene …
antiviral role by preventing viruses from traversing the cellular lipid bilayer. IFITM3 gene …
Cell-mediated immune responses to COVID-19 infection
A Guihot, E Litvinova, B Autran, P Debré… - Frontiers in …, 2020 - frontiersin.org
An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV),
subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City …
subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City …
Host genetic polymorphisms involved in long-term symptoms of COVID-19
W Udomsinprasert, N Nontawong… - Emerging Microbes & …, 2023 - Taylor & Francis
Host genetic polymorphisms are recognized as a critical determinant of diversity in clinical
symptoms of Coronavirus disease 2019 (COVID-19). Accordingly, this study aimed to …
symptoms of Coronavirus disease 2019 (COVID-19). Accordingly, this study aimed to …