Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

H Sies, VV Belousov, NS Chandel, MJ Davies… - … reviews Molecular cell …, 2022 - nature.com
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

[HTML][HTML] Role of oxidative stress in diabetic cardiomyopathy

B De Geest, M Mishra - Antioxidants, 2022 - mdpi.com
Type 2 diabetes is a redox disease. Oxidative stress and chronic inflammation induce a
switch of metabolic homeostatic set points, leading to glucose intolerance. Several diabetes …

The contribution of the exposome to the burden of cardiovascular disease

T Münzel, M Sørensen, O Hahad… - Nature Reviews …, 2023 - nature.com
Large epidemiological and health impact assessment studies at the global scale, such as
the Global Burden of Disease project, indicate that chronic non-communicable diseases …

The molecular link between oxidative stress, insulin resistance, and type 2 diabetes: A target for new therapies against cardiovascular diseases

A Andreadi, A Bellia, N Di Daniele, M Meloni… - Current opinion in …, 2022 - Elsevier
Abstract Type 2 Diabetes Mellitus (T2D) is a chronic disease with a pandemic incidence
whose pathogenesis has not yet been clarified. Raising evidence highlighted the role of …

[HTML][HTML] Lipid peroxidation as a hallmark of severity in COVID-19 patients

M Martín-Fernández, R Aller, M Heredia-Rodríguez… - Redox Biology, 2021 - Elsevier
Background Oxidative stress may be a key player in COVID-19 pathogenesis due to its
significant role in response to infections. A defective redox balance has been related to viral …

Biomarkers of oxidative stress tethered to cardiovascular diseases

P Panda, HK Verma, S Lakkakula… - Oxidative Medicine …, 2022 - Wiley Online Library
Cardiovascular disease (CVD) is a broad term that incorporated a group of conditions that
affect the blood vessels and the heart. CVD is a foremost cause of fatalities around the …

[HTML][HTML] Health position paper and redox perspectives-Disease burden by transportation noise

M Sørensen, G Pershagen, JD Thacher, T Lanki… - Redox Biology, 2023 - Elsevier
Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …

[HTML][HTML] Selenium, a micronutrient that modulates cardiovascular health via redox enzymology

DE Handy, J Joseph, J Loscalzo - Nutrients, 2021 - mdpi.com
Selenium (Se) is a trace nutrient that promotes human health through its incorporation into
selenoproteins in the form of the redox-active amino acid selenocysteine (Sec). There are 25 …

[HTML][HTML] From imbalance to impairment: the central role of reactive oxygen species in oxidative stress-induced disorders and therapeutic exploration

S Afzal, AS Abdul Manap, A Attiq… - Frontiers in …, 2023 - frontiersin.org
Increased production and buildup of reactive oxygen species (ROS) can lead to various
health issues, including metabolic problems, cancers, and neurological conditions. Our …

[HTML][HTML] Early detection is the best prevention—Characterization of oxidative stress in diabetes mellitus and its consequences on the cardiovascular system

S Rajlic, H Treede, T Münzel, A Daiber, GD Duerr - Cells, 2023 - mdpi.com
Previous studies demonstrated an important role of oxidative stress in the pathogenesis of
cardiovascular disease (CVD) in diabetic patients due to hyperglycemia. CVD remains the …