CREBBP alterations are associated with a poor prognosis in de novo AML

AJ Lamble, K Hagiwara, RB Gerbing… - Blood, The Journal …, 2023 - ashpublications.org
The cyclic adenosine monophosphate response elementbinding protein (CREBBP) gene is
located on chromosome 16p13 and encodes a histone acetyltransferase having the same …

Acute myeloid leukemia with t(8;16)(p11.2;p13.3)/KAT6A-CREBBP in adults

W Xie, S Hu, J Xu, Z Chen, LJ Medeiros, G Tang - Annals of hematology, 2019 - Springer
Abstract t (8; 16)(p11. 2; p13. 3)/KAT6A-CREBBP is a rare recurrent cytogenetic abnormality
associated with acute myeloid leukemia (AML). We report 15 cases with t (8; 16)(p11. 2; p13 …

Uncommon cytogenetic abnormalities identifying high-risk acute myeloid leukemia in children

R Masetti, SN Bertuccio, V Guidi, S Cerasi… - Future …, 2020 - Future Medicine
Pediatric acute myeloid leukemia (AML) represents an aggressive disease and is the
leading cause of childhood leukemic mortality. The genomic landscape of pediatric AML has …

Early-age acute leukemia: revisiting two decades of the Brazilian collaborative study group

MS Pombo-de-Oliveira, FG Andrade… - Archives of Medical …, 2016 - Elsevier
The understanding of leukemogenesis in early-age acute leukemia (EAL) has improved
remarkably. Initiating somatic mutations detected in dried neonatal blood spots (DNBS) and …

[HTML][HTML] Hemophagocytosis by blasts in a child with acute monocytic leukemia after chemotherapy

MG Farias, PAC Freitas, F Spagnol… - Revista Paulista de …, 2020 - SciELO Brasil
Objective: To describe the case of a child who presented hemophagocytic
lymphohistiocytosis (HLH) associated with acute monocytic leukemia after chemotherapy …

[HTML][HTML] Acute myeloid leukaemia at an early age: reviewing the interaction between pesticide exposure and KMT2A-rearrangement

MS Pombo-de-Oliveira, FG Andrade… - …, 2017 - ncbi.nlm.nih.gov
Acute myeloid leukaemia (AML) in early childhood is characterised by a high frequency of
recurrent genomic aberrations associated with distinct myeloid subtypes, clinical outcomes …

Genetics of acquired cytokine storm syndromes

GS Schulert, K Zhang - Cytokine Storm Syndrome, 2019 - Springer
Secondary hemophagocytic lymphohistiocytosis (sHLH) has historically been defined as a
cytokine storm syndrome (CSS) occurring in the setting of triggers leading to strong …

[HTML][HTML] HEMOFAGOCITOSE POR CÉLULAS BLÁSTICAS EM PACIENTE PEDIÁTRICO COM LEUCEMIA MONOCÍTICA AGUDA APÓS QUIMIOTERAPIA

MG Farias, PAC Freitas, F Spagnol… - Revista Paulista de …, 2020 - SciELO Brasil
Objetivo: Descrever um caso de um paciente pediátrico que apresentou linfo-histiocitose
hemofagocítica (LHH) associada à leucemia monocítica aguda pós-quimioterapia, com …

[PDF][PDF] Hemophagocytosis or emperipolesis by lymphoblast after rapid transformation of chronic myeloid leukemia

JL Cruz-Souza, FPD Carvalho, M Melo… - J Clin Images Med …, 2021 - jcimcr.org
A Male, 11-Years-Old, Admitted In March 2019 With Chronic myelogenous leukemia (CML)
in treatment with Imatinib. Three months after diagnosis in outpatient visit was observed …

Cannibalistic Hemophagocytosis in Acute Myeloid Leukemia with Trisomy 9

S Padhi, S Mishra, G Chhabra, A Panigrahi - Indian Journal of Hematology …, 2020 - Springer
A 45-year-old male patient was subjective to bone marrow examination for evaluation of 10-
day history of increasing fatigue secondary to severe anemia requiring packed red cell …