[HTML][HTML] Overcoming cancer therapeutic bottleneck by drug repurposing
Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …
the development of the alternative strategy of drug repurposing, the development of old …
[HTML][HTML] Apoptosis: a target for anticancer therapy
CM Pfeffer, ATK Singh - International journal of molecular sciences, 2018 - mdpi.com
Apoptosis, the cell's natural mechanism for death, is a promising target for anticancer
therapy. Both the intrinsic and extrinsic pathways use caspases to carry out apoptosis …
therapy. Both the intrinsic and extrinsic pathways use caspases to carry out apoptosis …
Curcumin, a golden spice with a low bioavailability
A Siviero, E Gallo, V Maggini, L Gori, A Mugelli… - Journal of Herbal …, 2015 - Elsevier
In recent years several drugs have been developed deriving from traditional products and
current drug research is actively investigating the possible therapeutic roles of many …
current drug research is actively investigating the possible therapeutic roles of many …
Curcumin supplementation in pediatric patients: A systematic review of current clinical evidence
This systematic review was designed to determine the clinical efficacy and safety of
curcumin supplementation for pediatric patients based on clinical trials in children. We …
curcumin supplementation for pediatric patients based on clinical trials in children. We …
[HTML][HTML] Targeted therapies of curcumin focus on its therapeutic benefits in cancers and human health: Molecular signaling pathway-based approaches and future …
The curry powder spices turmeric (Curcuma longa L.), which contains curcumin
(diferuloylmethane), an orange-yellow chemical. Polyphenols are the most commonly used …
(diferuloylmethane), an orange-yellow chemical. Polyphenols are the most commonly used …
[HTML][HTML] Nanoparticle curcumin ameliorates experimental colitis via modulation of gut microbiota and induction of regulatory T cells
M Ohno, A Nishida, Y Sugitani, K Nishino, O Inatomi… - PloS one, 2017 - journals.plos.org
Background and Aims Curcumin is a hydrophobic polyphenol derived from turmeric, a
traditional Indian spice. Curcumin exhibits various biological functions, but its clinical …
traditional Indian spice. Curcumin exhibits various biological functions, but its clinical …
Curcumin and cancer: barriers to obtaining a health claim
JG Devassy, ID Nwachukwu, PJH Jones - Nutrition reviews, 2015 - academic.oup.com
Curcumin is a highly pleiotropic molecule found in the rhizomes of Curcuma longa
(turmeric). It is responsible for the yellow color of turmeric and has been shown to inhibit the …
(turmeric). It is responsible for the yellow color of turmeric and has been shown to inhibit the …
Cancer chemoprevention by dietary phytochemicals: Epidemiological evidence
RB Ruiz, PS Hernández - Maturitas, 2016 - Elsevier
Background In recent years, natural compounds called “phytochemicals”, which are present
in fruits, vegetables, and plants, have received special attention due to their potential to …
in fruits, vegetables, and plants, have received special attention due to their potential to …
[HTML][HTML] Evaluation of curcumin loaded chitosan/PEG blended PLGA nanoparticles for effective treatment of pancreatic cancer
G Arya, M Das, SK Sahoo - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Pancreatic cancer is considered as one of the most lethal type of cancer with a poor 5-year
survival rate. Cancer metastasis represents one of the primary cause which limits therapy …
survival rate. Cancer metastasis represents one of the primary cause which limits therapy …
Phytosome complex of curcumin as complementary therapy of advanced pancreatic cancer improves safety and efficacy of gemcitabine: Results of a prospective …
D Pastorelli, ASC Fabricio, P Giovanis… - Pharmacological …, 2018 - Elsevier
A large body of biomedical evidence indicates that activation of Nrf2 by curcumin increases
the nucleophilic tone and damps inflammation cumulatively supporting the malignant …
the nucleophilic tone and damps inflammation cumulatively supporting the malignant …