Acetylated polysaccharides refer to polysaccharides containing acetyl groups on sugar
units. In the past, the acetylation modification of wall polysaccharides has been a hot …

Pancreatic ductal adenocarcinoma (PDA) has become one of the leading causes of cancer-
related deaths across the world. A lack of durable responses to standard-of-care …

The primary physiological process of respiration produces carbon dioxide (CO 2) that reacts
with water molecules which subsequently liberates bicarbonate (HCO–3) and protons …

Pancreatic ductal adenocarcinoma (PDAC) has one of the highest incidence/death ratios
among all neoplasms due to its late diagnosis and dominant chemoresistance. Most PDAC …

Background Gemcitabine resistance (GR) is a significant clinical challenge in pancreatic
adenocarcinoma (PAAD) treatment. Macrophages in the tumor immune-microenvironment …

Background Epidermal growth factor receptor (EGFR) is an essential target for cancer
treatment. However, EGFR inhibitor erlotinib showed limited clinical benefit in pancreatic …

Pancreatic ductal adenocarcinoma (PDAC) is considered one of the deadliest malignancies,
with dismal survival rates and extremely prevalent chemoresistance. Gemcitabine is one of …

Simple Summary Pancreatic cancer is the fourth leading cause of cancer-related mortality
worldwide. The poor survival associated with this disease is due to delayed diagnosis, a …

Bioengineering close‐to‐native in vitro models that emulate tumors bioarchitecture and
microenvironment is highly appreciable for improving disease modeling toolboxes. Herein …

Metabolic reprogramming is known as an emerging mechanism of chemotherapy
resistance, but the metabolic signatures of pancreatic ductal adenocarcinomas (PDACs) …