Lung disease encompasses acute, infectious processes and chronic, non-infectious
processes such as chronic obstructive pulmonary disease, asthma and lung cancer. People …

Despite the success of antiretroviral therapy (ART), people living with HIV continue to suffer
from high burdens of respiratory infections, lung cancers and chronic lung disease at a …

Cancer remains a significant global challenge, with an estimated 47% increase in cancer
patients from 2020 to 2040. Increasing research has identified microorganism as a risk factor …

Pneumonia imposes a significant clinical burden on people with immunocompromising
conditions. Millions of individuals live with compromised immunity because of cytotoxic …

Alveolar macrophages (AMs) are critical for defense against airborne pathogens and AM
dysfunction is thought to contribute to the increased burden of pulmonary infections …

Introduction Chronic lung disease is common among people living with HIV (PLWH). We
hypothesised that PLWH receiving antiretroviral therapy (ART) have faster lung function …

Background Prior studies have found that human immunodeficiency virus (HIV) infection is
associated with impaired lung function and increased risk of chronic lung disease, but few …

Macrophages can serve as a reservoir for human immunodeficiency-1 (HIV-1) virus in host
cells, constituting a barrier to eradication, even in patients who are receiving antiretroviral …

Culture-independent study of the lower respiratory tract after lung transplantation has
enabled an understanding of the microbiome–that is, the collection of bacteria, fungi, and …

People with HIV remain at greater risk for both infectious and non-infectious pulmonary
diseases even after antiretroviral therapy initiation and CD4 cell count recovery. These …