The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Growth factors belonging to the FGF family play important roles in tissue and organ repair
after trauma. In this review, I discuss the regulation by FGFs of the aspects of cellular …

Abstract Fibroblast growth factor 8 (FGF‐8), also known as androgen‐induced growth factor
(AIGF), is presumed to be a potent mitogenic cytokine that plays important roles in early …

Low nephron number—resulting, for example, from prematurity or developmental anomalies—
is a risk factor for the development of hypertension, chronic kidney disease and kidney …

The adult mammalian kidney is a poorly regenerating organ that lacks the stem cells that
could replenish functional homeostasis similarly to, eg, skin or the hematopoietic system …

Mammalian nephron endowment is determined by the coordinated cessation of
nephrogenesis in independent niches. Here we report that translatome analysis in Tsc1+ …

Notch signaling promotes maturation of nephron epithelia, but its proposed contribution to
nephron segmentation into proximal and distal domains has been called into doubt. We …

Diabetic nephropathy (DN) is a common microvascular complication in the late stages of
diabetes. Currently, the etiology and pathogenesis of DN are not well understood. Even so …

The kidney is among the best characterized developing tissues, with the genes and
signaling pathways that regulate embryonic and adult kidney patterning and development …

Kidneys develop via iterative branching of the ureteric epithelial tree and subsequent
nephrogenesis at the branch points. Nephrons form in the cap mesenchyme as the …