ABSTRACT Drug-Induced Liver Injury (DILI) constitutes hepatic damage attributed to drug
exposure. DILI may be categorized as hepatocellular, cholestatic or mixed and might also …

Acute liver injury (ALI) is a globally important public health issue that, when severe, rapidly
progresses to acute liver failure, seriously compromising the life safety of patients. The …

Vaccination is one of the most vigorous ways to intervene in the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) pandemic. Cases of autoimmune hepatitis (AIH) …

Due to concealment, high invasiveness and a lack of indicators, malignant tumors have
emerged as one of the deadliest diseases worldwide and their incidence is rising yearly …

Background & Aims Primary sclerosing cholangitis (PSC) is an immune-mediated
cholestatic liver disease for which there is an unmet need to understand the cellular …

Abstract Type 1 Innate Lymphoid cells (ILC1s) are tissue‐resident cells that partake in the
regulation of inflammation and homeostasis. A major feature of ILC1s is their ability to …

Liver fibrosis is a fibrogenic and inflammatory process that results from hepatocyte injury and
is characterized by hepatic architectural distortion and resultant loss of liver function. There …

Acute liver failure (ALF) is a severe liver disease caused by disruptions in the body's
immune microenvironment. In the early stages of ALF, Kupffer cells (KCs) become depleted …

Broccoli seed extract (BSE) is rich in glucoraphanin (GRP), which may be transformed by
intestinal microbes into sulforaphane (SFN), a compound with strong anti-inflammatory and …

The liver is a multifunctional organ that plays crucial roles in numerous physiological
processes, such as production of bile and proteins for blood plasma, regulation of blood …