Wilms' tumor gene 1: lessons from the interface between kidney development and cancer
E Torban, P Goodyer - American Journal of Physiology …, 2024 - journals.physiology.org
In 1990, mutations of the Wilms' tumor-1 gene (WT1), encoding a transcription factor in the
embryonic kidney, were found in 10–15% of Wilms' tumors; germline WT1 mutations were …
embryonic kidney, were found in 10–15% of Wilms' tumors; germline WT1 mutations were …
Genetic Studies Highlight the Role of TET2 and INO80 in DNA Damage Response and Kidney Disease Pathogenesis
Genome-wide association studies (GWAS) have identified over 800 loci associated with
kidney function, yet the specific genes, variants, and pathways involved remain elusive. By …
kidney function, yet the specific genes, variants, and pathways involved remain elusive. By …