The Role of Extracorporeal Photopheresis in the Management of Graft Versus Host Disease: Narrative Review

A Berhan, S Damtie, A Almaw, B Legesse… - ImmunoTargets and …, 2024 - Taylor & Francis
Hematopoietic stem cell donation is a method used to treat both blood-related and non-
blood-related malignancies. Graft-versus-host disease is a potentially life-threatening …

Extracorporeal photopheresis in graft-versus-host disease

PA Cantó, JS Caballer, PS Alcaína… - … and cellular therapy, 2023 - Elsevier
Graft-versus-host disease (GVHD) is a major cause of mortality and morbidity following
allogeneic hematopoietic stem cell transplantation. Extracorporeal photopheresis (ECP) …

Recent insights into extracorporeal photopheresis for graft-versus-host disease

C Del Fante, C Perotti - Expert Review of Clinical Immunology, 2024 - Taylor & Francis
ABSTRACT Introduction Extracorporeal Photopheresis (ECP) may be considered the unique
large-scale cell therapy currently available. It is currently employed mainly as second-line …

Apoptosis induction by extracorporeal photopheresis is enhanced by increasing the 8‐methoxypsoralen concentration and by replacing plasma with saline

V Hähnel, AM Brosig, M Ehrenschwender… - …, 2021 - Wiley Online Library
Background Extracorporeal photopheresis (ECP), an apheresis‐based therapy for various
immunological diseases, works mainly by inducing apoptosis in lymphocytes. Several …

Validation of an apoptosis assay for extracorporeal photopheresis

V Hähnel, F Dormann, K Kronenberg… - Transfusion …, 2021 - Wiley Online Library
Objectives This validation study investigated a flow cytometric apoptosis assay according to
good manufacturing practice (GMP). Background Extracorporeal photopheresis (ECP) is a …

Validation of a new automated irradiation system for off-line ECP

C Del Fante, C Klersy, E Barone, S De Vitis… - … and Apheresis Science, 2023 - Elsevier
Extracorporeal photopheresis (ECP) is a cell therapy originally employed for cutaneous T
cell lymphoma and later for GvHD, solid organ rejection and other immunological diseases …

Automated mononuclear cell collection: a feasibility study employing a new software for extracorporeal photopheresis

C Del Fante, L Scudeller, C Mortellaro… - Vox …, 2019 - Wiley Online Library
Background and objectives Very recently, Fresenius Kabi, improved the software (autoMNC
lymphocytes, SW 04.03. 08) for mononuclear cells (MNCs) collection with the aim to …

A simplified extracorporeal photopheresis procedure based on single high‐dose ultraviolet A light irradiation shows similar in vitro efficacy

V Buchele, H Hackstein - Transfusion, 2021 - Wiley Online Library
Background Extracorporeal photopheresis (ECP) is one of the most widely used and
effective cell‐based therapies for the treatment of T‐cell–mediated diseases. The patients' …

Matrix-dependent absorption of 8–methoxypsoralen in extracorporeal photopheresis

V Hähnel, I Weber, S Tuemmler, B Graf… - Photochemical & …, 2020 - Springer
Background: Extracorporeal photopheresis (ECP) is an effective immunomodulatory therapy
for various diseases. Autologous leukocytes are collected, photoactivated with a …

Optimierung der extrakorporalen Photopherese

V Hähnel, AM Brosig, R Burkhardt… - …, 2022 - thieme-connect.com
Die Extrakorporale Photopherese ist ein etabliertes Therapieverfahren für Patienten mit T-
Zell vermittelten Erkrankungen. Dabei besteht das Verfahren aus der Gewinnung autologer …