Nitric oxide (NO˙) is a short-lived, endogenously produced gas that is highly diffusible across
cell membranes and acts as a signaling molecule in the body. The redox state and chemistry …

Besides worthy development in cancer therapy, cancer is still one of the leading causes of
death, worldwide. The future burden of cancer will probably be even larger because people …

Cancer is a molecularly heterogeneous disease [1] and one of the major causes of death
worldwide. The existence of various types of tumours with different histopathologies, genetic …

Hybrid drug 1 (NO-ASA) continues to attract intense research from chemists and biologists
alike. It consists of ASA and a− ONO2 group connected through a spacer and is in …

The unique bioenergetic feature of cancer, aerobic glycolysis or the Warburg effect, is an
attractive therapeutic target for cancer therapy. Reversing the glycolytic phenotype may …

Abstract Higher cyclooxygenase 2 (COX-2) expression is often observed in aggressive
colorectal cancers (CRCs). Here, we attempt to examine the association between COX-2 …

Cancer prevention sometimes referred to as tertiary prevention or chemoprevention makes
use of specific xenobiotics or drugs to prevent, delay, or retard the development of cancer …

Nitric oxide is a key second messenger in most tissues, where it is generated at low
concentrations, predominantly by the catalytic action of two constitutively expressed isoforms …

Cancer is a type of human cell degenerative disease that has afflicted a large number of
people for years. Cancer is caused due to the abnormal proliferation of cells in any part of …

Nitric oxide (NO) a gaseous free radical is one of the ten smallest molecules found in nature,
while hydrogen sulfide (H 2 S) is a gas that bears the pungent smell of rotten eggs. Both are …