Background: Tendon and ligament injuries accounted for 30% of all musculoskeletal
consultations with 4 million new incidences worldwide each year and thus imposed a …

Decellularization is the process of removing the cellular components from tissues or organs.
It is a promising technology for obtaining a biomaterial with a highly preserved extracellular …

Currently available biomedical adhesives are mainly engineered to have one function (ie,
providing mechanical support for the repaired tissue). To improve the performance of …

Biologic scaffold materials composed of mammalian extracellular matrix are commonly used
in regenerative medicine and in surgical procedures for the reconstruction of numerous …

Tendon and ligament (TL) injuries affect millions of people annually. Biopolymers play a
significant role in TL tissue repair, whether the treatment relies on tissue engineering …

Biological scaffold materials composed of extracellular matrix (ECM) are routinely used for a
variety of clinical applications ranging from the treatment of chronic skin ulcers to hernia …

Driven by market demand, many biological and synthetic scaffolds have been developed
during the last 15 years. Both positive and negative results have been reported in clinical …

Dermal substitutes are of major importance in treating full thickness skin defects, both in
acute and chronic wounds. We outlined specific requirements of three classes of dermal …

Introduction Several biomaterials are available to bridge large tendon defects or reinforce
tenuous tendon repairs. Methods We performed a comprehensive search of PubMed …

The biological and physical augmentation provided by extracellular matrix (ECM) derived
implants continues to challenge and refine the conventional wisdom of biomaterials. It is …