Unveiling the Beauty of Cyclopropane Formation: A Comprehensive Survey of Enantioselective Michael Initiated Ring Closure (MIRC) Reactions

R Moorthy, W Biosawe, SS Thorat… - Organic Chemistry …, 2024 - pubs.rsc.org
This review presents a comprehensive overview of the synthesis of cyclopropanes using
enantioselective Michael Initiated Ring Closure (MIRC) reaction. Cyclopropane-containing …

Continuous Scalable Synthesis and Concentration Variation of Organozinc Compounds

L Gössl, K Dahms, G Menges-Flanagan… - … Process Research & …, 2024 - ACS Publications
In the production of pharmaceutically active ingredients, the formation of new carbon–
carbon bonds is essential. A widespread and frequently employed method is the use of …

Flow Chemistry of Metal Carbenoid Species towards Selective Organic Synthesis

K Okamoto, A Nagaki - Synthesis, 2024 - thieme-connect.com
This review deals with C1 carbenoid chemistry, with a focus on lithium carbenoid species
generated in flash flow systems. Strict control of the temperature, residence time, and mixing …