Recent advances in the development of pharmacologically active compounds that contain a benzoxazole scaffold
S Singh, G Veeraswamy, D Bhattarai… - Asian Journal of …, 2015 - Wiley Online Library
In recent years, the emergence of biologically active compounds that contain a heterocyclic
ring has gained a great deal of attention among medicinal chemists. Among these …
ring has gained a great deal of attention among medicinal chemists. Among these …
IL-17A and IL-17F orchestrate macrophages to promote lung cancer
N Ferreira, I Mesquita, F Baltazar, R Silvestre… - Cellular Oncology, 2020 - Springer
Purpose Previously, inflammation has been found to be associated with the development of
lung cancer. Despite their well-characterized pro-inflammatory functions, the putative roles …
lung cancer. Despite their well-characterized pro-inflammatory functions, the putative roles …
Selection signatures analysis reveals genes associated with high-altitude adaptation in Tibetan goats from Nagqu, Tibet
M Jin, J Lu, X Fei, Z Lu, K Quan, Y Liu, M Chu, R Di… - Animals, 2020 - mdpi.com
Simple Summary In the process of domestication, goats have undergone long-term artificial
and natural selection, leading to differences among goat breeds and leaving different …
and natural selection, leading to differences among goat breeds and leaving different …
Role of microRNA in metabolic shift during heart failure
MV Pinti, QA Hathaway… - American Journal of …, 2017 - journals.physiology.org
Heart failure (HF) is an end point resulting from a number of disease states. The prognosis
for HF patients is poor with survival rates precipitously low. Energy metabolism is centrally …
for HF patients is poor with survival rates precipitously low. Energy metabolism is centrally …
Tissue-specific orchestration of gilthead sea bream resilience to hypoxia and high stocking density
JA Martos-Sitcha, P Simó-Mirabet… - Frontiers in …, 2019 - frontiersin.org
Two different O2 levels (normoxia: 75–85% O2 saturation; moderate hypoxia: 42–43% O2
saturation) and stocking densities (LD: 9.5, and HD: 19 kg/m3) were assessed on gilthead …
saturation) and stocking densities (LD: 9.5, and HD: 19 kg/m3) were assessed on gilthead …
HIF‐1α Regulated WTAP Overexpression Promoting the Warburg Effect of Ovarian Cancer by m6A‐Dependent Manner
Y Lyu, Y Zhang, Y Wang, Y Luo… - Journal of …, 2022 - Wiley Online Library
N6‐methyladenosine (m6A) RNA methylation has been determined to execute crucial
functions in tumorigenesis and cancer development. WT1‐associated protein (WTAP) has …
functions in tumorigenesis and cancer development. WT1‐associated protein (WTAP) has …
[HTML][HTML] The effect of the tumor microenvironment and tumor-derived metabolites on dendritic cell function
JH Lee, SY Choi, NC Jung, JY Song, HG Seo… - Journal of …, 2020 - ncbi.nlm.nih.gov
Dendritic cells (DCs) have a critical effect on the outcome of adaptive immune responses
against growing tumors. Recent studies on the metabolism on DCs provide new insights on …
against growing tumors. Recent studies on the metabolism on DCs provide new insights on …
Osteoblasts impair cholesterol synthesis in chondrocytes via Notch1 signalling
Y Yang, D Zhang, D Guo, J Li, S Xu, J Wei… - Cell …, 2021 - Wiley Online Library
Objectives Previous reports have proposed the importance of signalling and material
exchange between cartilage and subchondral bone. However, the specific experimental …
exchange between cartilage and subchondral bone. However, the specific experimental …
Quantitative global proteome and lysine succinylome analyses provide insights into metabolic regulation and lymph node metastasis in gastric cancer
Y Song, J Wang, Z Cheng, P Gao, J Sun, X Chen… - Scientific reports, 2017 - nature.com
With the rapid development of high-throughput quantitative proteomic and transcriptomic
approaches, the molecular mechanisms of cancers have been comprehensively explored …
approaches, the molecular mechanisms of cancers have been comprehensively explored …
Resistance to anoikis in transcoelomic shedding: The role of glycolytic enzymes
RB Wilson, W Solass, R Archid, FJ Weinreich… - Pleura and …, 2019 - degruyter.com
Detachment of cells from the extracellular matrix into the peritoneal cavity initiates a cascade
of metabolic alterations, leading usually to cell death by apoptosis, so-called anoikis …
of metabolic alterations, leading usually to cell death by apoptosis, so-called anoikis …