General anaesthesia is usually considered to safely induce a reversible brain state allowing
the performance of surgery under optimal conditions. An increasing number of clinical and …

Hypospadias is one of the most common congenital anomalies in men. The condition is
typically characterized by proximal displacement of the urethral opening, penile curvature …

Background In laboratory animals, exposure to most general anaesthetics leads to
neurotoxicity manifested by neuronal cell death and abnormal behaviour and cognition …

Background Few studies of how exposure of children to anesthesia may affect
neurodevelopment employ comprehensive neuropsychological assessments. This study …

Importance Exposure of young animals to commonly used anesthetics causes neurotoxicity
including impaired neurocognitive function and abnormal behavior. The potential …

Anesthesia and Developing Brains — Implications of the FDA Warning | NEJM Skip to main
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The potential for commonly used anesthetics and sedatives to cause neuroapoptosis and
other neurodegenerative changes in the developing mammalian brain has become evident …

Background Exposure of young animals to general anesthesia causes neurodegeneration
and lasting behavioral abnormalities; whether these findings translate to children remains …

Importance The results of preclinical studies suggest that anesthetic drugs administered to
neonatal animals cause widespread neuronal apoptosis and later neurocognitive …

Anesthetic agents disrupt neurodevelopment in animal models, but evidence in humans is
mixed. The morphologic and behavioral changes observed across many species predicted …