Alzheimer's disease (AD) is an age‐associated neurodegenerative disorder with
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …

Cognitive dysfunction is increasingly recognized as an important comorbidity of diabetes
mellitus. Different stages of diabetes-associated cognitive dysfunction exist, each with …

Abstract Characterization of the genetic landscape of Alzheimer's disease (AD) and related
dementias (ADD) provides a unique opportunity for a better understanding of the associated …

Due to the progressive aging of the population, Alzheimer's disease (AD) is becoming a
healthcare burden of epidemic proportions for which there is currently no cure …

We identified rare coding variants associated with Alzheimer's disease in a three-stage case–
control study of 85,133 subjects. In stage 1, we genotyped 34,174 samples using a whole …

The term vascular cognitive impairment (VCI) was introduced around the start of the new
millennium and refers to the contribution of vascular pathology to any severity of cognitive …

Although the prevalence of dementia continues to increase worldwide, incidence in the
western world might have decreased as a result of better vascular care and improved brain …

Dementia is an increasing focus for policymakers, civil organizations and multidisciplinary
researchers. The most recent descriptive epidemiological research into dementia is …

CSF biomarkers, including total-tau, neurofilament light chain (NfL) and amyloid-β, are
increasingly being used to define and stage Alzheimer's disease. These biomarkers can be …

Nucleation of new peptide and protein aggregates on the surfaces of amyloid fibrils of the
same peptide or protein has emerged in the past two decades as a major pathway for both …