[HTML][HTML] Longitudinal change of gut microbiota in hypertensive disorders in pregnancy: a nested case–control and Mendelian randomization study

X Wu, Q Li, J Cai, H Huang, S Ma, H Tan - Scientific Reports, 2023 - nature.com
Mounting evidence has shown that gut microbiota (GM) is related to hypertensive disorders
in pregnancy (HDP), however, most studies only focused on one time point in pregnancy. In …

The effect of L-carnitine on critical illnesses such as traumatic brain injury (TBI), acute kidney injury (AKI), and hyperammonemia (HA)

B Sharma, L Schmidt, C Nguyen, S Kiernan… - Metabolites, 2024 - mdpi.com
L-carnitine (LC) through diet is highly beneficial for critical patients. Studies have found that
acetyl-L-carnitine (ALC) can reduce cerebral edema and neurological complications in TBI …

A small, polyphyletic group of Firmicutes synthesizes trimethylamine from l‐carnitine

M Vital, Y Heinrich‐Sanchez - Mlife, 2023 - Wiley Online Library
Impact statement Gut microbiota‐derived trimethylamine (TMA) is associated with
cardiometabolic disorders and exemplifies a microbial involvement in the etiology of …

Physiopathological mechanisms involved in the development of hypertension associated with gut dysbiosis and the effect of nutritional/pharmacological interventions

VMM Giménez, NLR Mikusic, HJ Lee… - Biochemical …, 2022 - Elsevier
The gut microbiota dysbiosis represents a triggering factor for cardiovascular diseases,
including hypertension. In addition to the harmful impact caused by hypertension on different …

[HTML][HTML] Gut microbiota in sarcopenia and heart failure

CF Liu, WHW Tang - The journal of cardiovascular aging, 2022 - ncbi.nlm.nih.gov
Sarcopenia is common in aging and in patients with heart failure (HF) who may experience
worse outcomes. Patients with muscle wasting are more likely to experience falls and can …

Targeted curation of the gut microbial gene content modulating human cardiovascular disease

MA Borton, M Shaffer, DW Hoyt, R Jiang… - Mbio, 2023 - Am Soc Microbiol
Despite the promise of the gut microbiome to predict human health, few studies expose the
molecular-scale processes underpinning such forecasts. We mined over 200,000 gut …

Human gut microbiome researches over the last decade: current challenges and future directions

H Wu, S Forslund, Z Wang, G Zhao - Phenomics, 2023 - Springer
Over the last decade, significant progress has been made in understanding the evolutionary,
ecological, and metabolic significance of the gut microbiota for human health. This …

Trimethylamine N-Oxide and Related Gut Microbe-Derived Metabolites and Incident Heart Failure Development in Community-Based Populations

WHW Tang, RN Lemaitre, PN Jensen… - Circulation: Heart …, 2024 - ahajournals.org
BACKGROUND: Growing evidence indicates that trimethylamine N-oxide, a gut microbial
metabolite of dietary choline and carnitine, promotes both cardiovascular disease and …

Serum L-carnitine levels are associated with first stroke in Chinese adults with hypertension

Z Zhou, N Zhang, Y Song, L Liu, J Li, Y Zhang, Y Huo… - Stroke, 2022 - Am Heart Assoc
Background: This study aimed to evaluate the association of serum L-carnitine with first
stroke and explore potential effect modifiers. Methods: This is a nested, case-control study …

Sweet, bloody consumption–what we eat and how it affects vascular ageing, the BBB and kidney health in CKD

A Schwarz, L Hernandez, S Arefin, E Sartirana… - Gut …, 2024 - Taylor & Francis
In today's industrialized society food consumption has changed immensely toward
heightened red meat intake and use of artificial sweeteners instead of grains and vegetables …