Granulocytes are innate immune effector cells with essential functions in host resistance to
bacterial infections. I will discuss emerging evidence that during Mycobacterium tuberculosis …

Tuberculosis (TB) drug discovery and development has undergone nothing short of a
revolution over the past 20 years. Successful public–private partnerships and sustained …

Background Immune control of Mycobacterium tuberculosis (Mtb) infection is largely
influenced by the extensive disease heterogeneity that is typical for tuberculosis (TB). In this …

Tuberculosis (TB) is a highly contagious bacterial infection caused by Mycobacterium
tuberculosis (Mtb), which has been ranked as the second leading cause of death worldwide …

Abstract Tuberculosis (TB) accounts for 1.6 million deaths annually and over 25% of deaths
due to antimicrobial resistance. Mycobacterium tuberculosis (M. tb) drives MCL-1 expression …

Introduction Tuberculosis remains a significant concern in global public health due to its
intricate biology and propensity for developing antibiotic resistance. Discovering new drugs …

Mycobacterium tuberculosis complex causes tuberculosis (TB), a disease that causes
pulmonary inflammation but can also affect other tissues. Despite macrophages having a …

Considering the large spectrum of side effects caused by synthetic drugs and the
development of natural alternatives utilizing Algerian flora, this study aimed to place a …

P-glycoprotein (encoded by the ABCB1 gene) has a dual role in regulating inflammation and
reducing chemotherapy efficacy in various diseases, but there are few studies focused on …

Introduction During infection, bone marrow (BM) hematopoiesis is reprogrammed toward
myeloid cell production, a mechanism named emergency myelopoiesis. In addition to …