Chondrocytes are responsible for the maintenance of the articular cartilage. A loss of
homeostasis in cartilage contributes to the development of osteoarthritis (OA) when the …

Nanozymes refer to nanomaterials that catalyze enzyme substrates into products under
relevant physiological conditions following enzyme kinetics. Compared to natural enzymes …

Osteoarthritis (OA) is the major course of joint deterioration, in which M1 macrophage-driven
synovitis exacerbates the pathological process. However, precise therapies for M1 …

Human cells have to deal with the constant production of reactive oxygen species (ROS).
Although ROS overproduction might be harmful to cell biology, there are plenty of data …

Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …

Cartilage-targeting delivery of therapeutic agents is still an effective strategy for osteoarthritis
(OA) therapy. Recently, scavenging for reactive oxygen species (ROS) and activating …

Background: Osteoarthritis (OA) is a common degenerative joint disease. The pathogenesis
of OA is closely related to inflammatory responses and apoptosis of chondrocytes …

Osteoarthritis (OA), characterized by cartilage erosion, synovium inflammation, and
subchondral bone remodeling, is a common joint degenerative disease worldwide. OA …

Osteoarthritis (OA) is a common articular degenerative disease characterized by loss of
cartilage matrix and subchondral bone sclerosis. Kartogenin (KGN) has been reported to …

Osteoarthritis (OA) is one of the most common musculoskeletal disorders worldwide.
Oxidative stress initiated by excessive free radicals such as reactive oxygen species (ROS) …