The role of serotonin in depression and antidepressant treatment remains unresolved
despite decades of research. In this paper, we make three major claims. First, serotonin …

Although the early antidepressant trials which included severely ill and hospitalized patients
showed substantial drug‐placebo differences, these robust differences have not held up in …

A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Background Psoriasis has substantial psychological and emotional effects. We assessed the
effect of etanercept, an effective treatment for the clinical symptoms of psoriasis, on fatigue …

Importance Long-term longitudinal studies are needed to delineate the trajectory of
depressive symptoms across adulthood and to individuate factors that may contribute to …

Objective The aim of this study was to review the effects of vitamin D supplementation on
depressive symptoms in randomized controlled trials. Although low vitamin D levels have …

Major depressive disorder (MDD) is a common mood disorder that can result in significant
discomfort as well as interpersonal and functional disability. A growing body of research …

These British Association for Psychopharmacology guidelines cover the range and aims of
treatment for anxiety disorders. They are based explicitly on the available evidence and are …

A revision of the 2000 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken to …

Context The need for improved therapeutic agents that more quickly and effectively treat
depression is critical. In a pilot study we evaluated the role of the cholinergic system in …