The long-sought discovery of HER2 as an actionable and highly sensitive therapeutic target
was a major breakthrough for the treatment of highly aggressive HER2-positive breast …

Traditionally, vaccines have helped eradication of several infectious diseases and also
saved millions of lives in the human history. Those prophylactic vaccines have acted through …

Breast cancer (BC) is the most common cancer in women worldwide. Although substantial
progress has been made in the diagnosis and treatment of breast cancer, the efficacy and …

Cell therapy has reached significant milestones in various life-threatening diseases,
including cancer. Cell therapy using fluorescent and radiolabeled chimeric antigen receptor …

Breast cancer, the most frequent female malignancy, is often curable when detected at an
early stage. The treatment of metastatic breast cancer is more challenging and may be …

Simple Summary Although immune check point inhibitors have been established as a new
paradigm in cancer treatment, they have shown no clinical benefit in immune excluded or …

Since the discovery of dendritic cells (DCs) in 1973 by Ralph Steinman, a tremendous
amount of knowledge regarding these innate immunity cells has been accumulating. Their …

Opinion statement The primary objective of this study is to evaluate the effectiveness of
cancer vaccines containing genetically modified dendritic cells (DCs) in inducing …

Background Despite advances in checkpoint inhibitor (CPI) therapy for cancer treatment,
many cancers remain resistant. Tumors deemed “cold” based on lack of T cell infiltration …