Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system

M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …

Neuropharmacological modulation of N-methyl-D-aspartate, noradrenaline and endocannabinoid receptors in fear extinction learning: Synaptic transmission and …

S Battaglia, C Di Fazio, CM Vicario… - International Journal of …, 2023 - mdpi.com
Learning to recognize and respond to potential threats is crucial for survival. Pavlovian
threat conditioning represents a key paradigm for investigating the neurobiological …

Editorial of special issue 'dissecting neurological and neuropsychiatric diseases: Neurodegeneration and neuroprotection'

M Tanaka, L Vécsei - International journal of molecular sciences, 2022 - mdpi.com
This Special Issue has focused on dissecting the neuroprotective and neurodegenerative
components of neurological and neuropsychiatric diseases, highlighting the latest advance …

Neural correlates and molecular mechanisms of memory and learning

S Battaglia, A Avenanti, L Vécsei, M Tanaka - International journal of …, 2024 - mdpi.com
Memory and learning are essential cognitive processes that enable us to obtain, retain, and
recall information. These factors are crucial for survival, adaptation, and creativity. However …

On making (and turning adaptive to) maladaptive aversive memories in laboratory rodents

L Gazarini, CAJ Stern, LJ Bertoglio - Neuroscience & Biobehavioral …, 2023 - Elsevier
Fear conditioning and avoidance tasks usually elicit adaptive aversive memories. Traumatic
memories are more intense, generalized, inflexible, and resistant to attenuation via …

Effects of a True Prophylactic Treatment on Hippocampal and Amygdala Synaptic Plasticity and Gene Expression in a Rodent Chronic Stress Model of Social Defeat

ET Winzenried, AC Everett, ER Saito, RM Miller… - International Journal of …, 2023 - mdpi.com
Post-traumatic stress disorder (PTSD) is a complex stress-related disorder induced by
exposure to traumatic stress that is characterized by symptoms of re-experiencing …

[HTML][HTML] Glucocorticoids modulate neural activity via a rapid non-genomic effect on Kv2. 2 channels in the central nervous system

Y Wang, Y Zhang, J Hu, C Pan, Y Gao, Q Liu, W Xu… - Neurobiology of …, 2024 - Elsevier
Glucocorticoids are primary stress hormones that exert neuronal effects via both genomic
and non-genomic signaling pathways. However, their rapid non-genomic effects and …

Mifepristone as a pharmacological intervention for stress‐induced alcohol craving: A human laboratory study

CL Haass‐Koffler, M Magill, N Cannella… - Addiction …, 2023 - Wiley Online Library
Preclinical and clinical work suggests that mifepristone may be a viable treatment for alcohol
use disorder (AUD). This was a Phase 1/2, outpatient, cross‐over, randomized, double …

The role of estrogen receptor manipulation during traumatic stress on changes in emotional memory induced by traumatic stress

M Biddle, D Knox - Psychopharmacology, 2023 - Springer
Rationale Traumatic stress leads to persistent fear, which is a core feature of post-traumatic
stress disorder (PTSD). Women are more likely than men to develop PTSD after trauma …

Basal forebrain cholinergic systems as circuits through which traumatic stress disrupts emotional memory regulation

D Knox, V Parikh - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Contextual and spatial systems facilitate changes in emotional memory regulation brought
on by traumatic stress. Cholinergic basal forebrain (chBF) neurons provide input to …