Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system
M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …
Neuropharmacological modulation of N-methyl-D-aspartate, noradrenaline and endocannabinoid receptors in fear extinction learning: Synaptic transmission and …
S Battaglia, C Di Fazio, CM Vicario… - International Journal of …, 2023 - mdpi.com
Learning to recognize and respond to potential threats is crucial for survival. Pavlovian
threat conditioning represents a key paradigm for investigating the neurobiological …
threat conditioning represents a key paradigm for investigating the neurobiological …
Editorial of special issue 'dissecting neurological and neuropsychiatric diseases: Neurodegeneration and neuroprotection'
This Special Issue has focused on dissecting the neuroprotective and neurodegenerative
components of neurological and neuropsychiatric diseases, highlighting the latest advance …
components of neurological and neuropsychiatric diseases, highlighting the latest advance …
Neural correlates and molecular mechanisms of memory and learning
Memory and learning are essential cognitive processes that enable us to obtain, retain, and
recall information. These factors are crucial for survival, adaptation, and creativity. However …
recall information. These factors are crucial for survival, adaptation, and creativity. However …
On making (and turning adaptive to) maladaptive aversive memories in laboratory rodents
Fear conditioning and avoidance tasks usually elicit adaptive aversive memories. Traumatic
memories are more intense, generalized, inflexible, and resistant to attenuation via …
memories are more intense, generalized, inflexible, and resistant to attenuation via …
Effects of a True Prophylactic Treatment on Hippocampal and Amygdala Synaptic Plasticity and Gene Expression in a Rodent Chronic Stress Model of Social Defeat
ET Winzenried, AC Everett, ER Saito, RM Miller… - International Journal of …, 2023 - mdpi.com
Post-traumatic stress disorder (PTSD) is a complex stress-related disorder induced by
exposure to traumatic stress that is characterized by symptoms of re-experiencing …
exposure to traumatic stress that is characterized by symptoms of re-experiencing …
[HTML][HTML] Glucocorticoids modulate neural activity via a rapid non-genomic effect on Kv2. 2 channels in the central nervous system
Y Wang, Y Zhang, J Hu, C Pan, Y Gao, Q Liu, W Xu… - Neurobiology of …, 2024 - Elsevier
Glucocorticoids are primary stress hormones that exert neuronal effects via both genomic
and non-genomic signaling pathways. However, their rapid non-genomic effects and …
and non-genomic signaling pathways. However, their rapid non-genomic effects and …
Mifepristone as a pharmacological intervention for stress‐induced alcohol craving: A human laboratory study
CL Haass‐Koffler, M Magill, N Cannella… - Addiction …, 2023 - Wiley Online Library
Preclinical and clinical work suggests that mifepristone may be a viable treatment for alcohol
use disorder (AUD). This was a Phase 1/2, outpatient, cross‐over, randomized, double …
use disorder (AUD). This was a Phase 1/2, outpatient, cross‐over, randomized, double …
The role of estrogen receptor manipulation during traumatic stress on changes in emotional memory induced by traumatic stress
M Biddle, D Knox - Psychopharmacology, 2023 - Springer
Rationale Traumatic stress leads to persistent fear, which is a core feature of post-traumatic
stress disorder (PTSD). Women are more likely than men to develop PTSD after trauma …
stress disorder (PTSD). Women are more likely than men to develop PTSD after trauma …
Basal forebrain cholinergic systems as circuits through which traumatic stress disrupts emotional memory regulation
Contextual and spatial systems facilitate changes in emotional memory regulation brought
on by traumatic stress. Cholinergic basal forebrain (chBF) neurons provide input to …
on by traumatic stress. Cholinergic basal forebrain (chBF) neurons provide input to …